Scientist Profile

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Agnes Llamasares Castillo

Pharmacist, DOST-SEI Scholarship award (2013)

Expertise: Pharmacy, Preformulation, Formulation, Immunopharmacology, Clinical trial, Product preformulation and Formulation of natural products, Preclinical/ clinical studies of formulated drugs and natural products, Product Stability Studies, Scabies And Immunological response in Scabies

Affiliation

Assistant Professor I, University of Santo Tomas, Faculty of Pharmacy, Main Bldg., España, Manila 1008

Assistant Professor, University of Santo Tomas, M.S. Pharmacy Program, The Graduate School

Resident Researcher, University of Santo Tomas, Research Cluster for the Natural and Applied Sciences, Thomas Aquinas Research Center

Association

    • Philippine Pharmaceutical Research Congress, Chair, Scientific Committee
    • National Research Council of the Philippines, Member
    • Philippine Association of Colleges of Pharmacy, Member
    • Natural Products Society of the Philippines, Member
    • Philippine Pharmaceutical Association, Member

Employment

    • Faculty of Pharmacy, University of Santo Tomas, Faculty member, 2006 - present
    • RCNAS, University of Santo Tomas, Resident Researcher, 2014 - present
    • Faculty of Pharmacy, University of Santo Tomas, Teaching Assistant, 2003 - 2005
    • Premiere Review Center, Reviewer / Lecturer, 2005 - 2008
    • INRESS Review Center, Reviewer / Lecturer, 2003 - 2006

Award

    • Dr. Alfredo C Santos Lecture Award (for Tinospora cordifolia Lotion: An Antiscabies and Immunomodulatory agent in Sarcoptes scabiei var hominis-Infected Pediatric Patients), 19th Natural Products Society of The Philippines Convention, 2014
    • DOST-SEI Scholarship award, Department of Science and Technology, 2013
    • DOST-SEI Scholarship (2 years), Department of Science and Technology, 2010 - 2012
    • First prize Paper poster presentation (for Randomized Assessor Blind Clinical trial on the safety and efficacy of the Aromatic oil shampoo vs 1% Permethrin shampoo in the treatment of pediculosis capitis), 20th Regional Conference of Dermatology, 2012
    • 1st Place, 16th Annual Residents Research Forum (Randomized Assessor Blind Clinical trial on the safety and efficacy of the Aromatic oil shampoo vs 1% Permethrin shampoo in the treatment of pediculosis capitis), Philippine Dermatological Society, UST, 2011
    • 2nd Place, UST Hospital Research Contest (Randomized Assessor Blind Clinical trial on the safety and efficacy of the Aromatic oil shampoo vs 1% Permethrin shampoo in the treatment of pediculosis capitis), Philippine Dermatological Society, 2011
    • 1st Place , UST Hospital Research Contest (A Double-Blind, Randomized Controlled Clinical trial on the safety and Effectiveness of 50% Tinospora rumphii Boerl (Makabuhay) lotion vs 5 % Permethrin Lotion in the Treatment of Scabies), Dept. of Medical Education and Research, UST Hospital, 2010
    • Most Outstanding Research Paper (Experimental Category, 2nd Place), Philippine Dermatological Society, 2010
    • Cum Laude (M.S. Pharmacy), UST Graduate School, 2006
    • Top 2, Pharmacy Licensure Exam, Professional Regulation Commision, 2003
    • Silver Medal, Philippine Association of Colleges of Pharmacy, 2003
    • Cum Laude (B.S. Pharmacy), University of Santo Tomas, Manila, 2002
    • Cum Laude (B.S. Botany), University of Santo Tomas, Manila, 2000

Research

    • Anti-scabies activities of Tinospora rumphii Boerl lotion in Sarcoptes scabeie var hominis–infected patients: A Pilot study [Completed]
    • Immunomodulatory effect of Tinospora rumphii Boerl lotion in Sarcoptes scabeie var hominis–infected patients and its predicted shelf life: A Pilot study [Completed]
    • A Double-Blind, Randomized Controlled Clinical trial on the safety and Effectiveness of 50% Tinospora rumphii Boerl. (Makabuhay) lotion vs 5% Permethrin Lotion in the Treatment of Scabies [Completed]
    • Randomized Assessor Blind Clinical trial on the safety and efficacy of the Aromatic oil shampoo vs 1% Permethrin shampoo in the treatment of pediculosis capitis [Completed]
    • Screening of the Anti-Oxidant Activity of the Fractionolic Extract of Tinospora cordifolia Stems [Completed]
    • Gel trial formulations of the Tinospora cordifolia Boerl Ethanolic extract [Ongoing]
    • Coating of Tinospora lotion with titanium dioxide [Ongoing]
    • COX I And COX II inhibition, TLC profiles of the different Tinospora cordifolia Boerl stem extracts [Ongoing]

Education

    • University of Santo Tomas, España, 1008 Manila, Doctor of Philosophy in Pharmacy, 2012
    • University of Santo Tomas, España, 1008 Manila, Master of Science in Pharmacy (Cum Laude), 2006
    • University of Santo Tomas, España, 1008 Manila, Bachelor of Science in Pharmacy (Cum Laude), 2002
    • University of Santo Tomas, España, 1008 Manila, Bachelor of Science in Botany (Cum Laude), 2000

Publication

    • Castillo, A.L., Ramos, J.D.A., De Francia, J.L., Quilala, P.F., & Dujunco, M.U., (2014) Immunomodulatory Effects Of Tinospora Cordifolia Lotion On Interleukin-1, Interleukin-6 And Interleukin-8 Levels In Scabies-Infected Pediatric Patients: A Single Blind, Randomized Trial
    • International Journal of Pharmaceutical Science and Drug Research Volume 6, No. 3
    • Castillo, A., Osi, M., Ramos, J.D., De Francia, J., Dujunco, M., & Quilala, P., (2013) Efficacy and Safety of Tinospora cordifolia Boerl Lotion in Sarcoptes scabiei var hominis-Infected Pediatric Patients: A Single blind, Randomized Controlled Trial
    • Journal of Pharmacology and Pharmacotherapeutics Volume 4, No. 1
    • Perez-Chua, T.A.P., Paliza, A.C., & Castillo, A.L., (2012) Randomized, assessor-blind Clinical trial on the safety and efficacy of the Aromatic oil shampoo vs 1% Permethrin shampoo in the treatment of pediculosis capitis
    • Philippine Journal of Dermatological Society Volume 21, No. 2
    • Castillo, A.L., Osi, M.O., Ramos, J.D.A., De Francia, J.L., Dyjunco, M.U., & Quilala, P.F., (2012) Immunomodulatory effect of Tinospora rumphii Boerl lotion in Sarcoptes scabiei var hominis-infected patients and its predicted shelf life:a pilot study
    • Transactions of the National Academy of Science and Technology Volume 34, No. 1
    • Mamaril, T.V., Osi, M.O., Ramos, J.D.A., De Francia, J.L., Dyjunco, M.U., Quilala, P.F., Manlusoc, J.K.T., Marcelo, A.L.C., Mendoza, M.C.C., Naga, M.V.D., Ng Sinco, J.W., Perez, T.A.P., & Castillo, A.L., (2012) Pediculicidal activity of a shampoo formulated from the crude ethanolic extract of Tinospora rumphii Boerl (menispermaceae) stems
    • Transactions of the National Academy of Science and Technology Volume 34, No. 1

Trainings

    • Pharmacy Practice Standards: Based on Science, Driven by Evidence, 2015 April 22-26, 2015 PPhA National Convention, SMX Convention Center, Bacolod City
    • Translational Research in Outcome based Pharmacy Education: A Training Workshop, 2014 October 22-23, PACOP’s FDS
    • PCHRD and DOST “Initiatives on Drug Discovery” Is the Philippines Catching Up?, 2014 July 24, SMX Convention Center, Pasay City
    • Engaging the Pharmacy in the Control of Tuberculosis, 2014 April 30, Pharmacy DOTS Initiative given by USAID at Chef Patrick’s Restaurant, Caloocan City
    • Training Workshop on Principles of Health Research Ethics and Good Clinical Practice, 2013 November 11-12, UPM-NIH and Metro Manila Health research and Dev't Consortium, CME Auditorium, UST
    • 2013 Faculty Development Seminar “Leadership and Effective Communication-Moving Knowledge to Action”, 2013 October 24-26, Sponsored by Philippine Association of Colleges of Pharmacy at Adamson University, Manila
    • PCR Basics and V3 Western Workflow Training, 2013 September 4-5, Faculty of Pharmacy, UST
    • LabTEC 2014: Addressing the Impact, Issues, and Challenges of AEC 2015 to Philippines’ Laboratories, 2014 June 17-18, R&D and Industries, Palawan Room, EDSA Shangri-La Hotel, Mandaluyong City
    • Investigatory Projects in Molecular Biology, 2010 October 21-22, College of Science, University of Santo Tomas
    • Seminar Workshop on Laboratory Animal Use and Handling, 2010 August 18
    • Spectrophotometric Calibration Standards and an Ultra-Micro Cell For UV/Vis Analysis of Proteins and Nucleic acids, 2009 August 10, Richmonde Hotel, Pasig City
    • Seminar on implementation of A.O. No. 56 s. 1989 Licensing of Drug Outlets, 2009 July 31, Malolos, Bulacan