Scientist Profile

Photo

Elsie C. Jimenez

Expertise: Biochemistry of Peptides and their Functional Effect, Toxicology, Biological Sciences, Peptide and Protein Biochemistry, Chemical Sciences, Biochemistry, Molecular Biology

Affiliation

Professor of Chemistry, Dept. of Physical Sciences, College of Science, University of the Philippines, Baguio City

Director, Cordillera Studies Center

Association

    • National Research Council of the Philippines, Member
    • Philippine Science Letters, Editorial Board Member
    • Philippine Biotechnology Venture Summit, Judge for Poster Session
    • Philippine Biotechnology for Venture Summit, Reviewer

Award

    • CHED Republica Zonal Award for Region 1, 2 and CAR, CHED, 2005
    • President's Academic Distinction Awards for International Publications 1999-2005, UP, 2005
    • UP Diamond Jubilee Professorial Chair in Chemistry, UP, 2005
    • Research Fellowship, University of Utah, Salt Lake City, 2005
    • Best Researcher Award, Philippine Society for Biochemistry and Molecular Biology, 2006-2008
    • UP International Publication Award, UP Baguio, 2006
    • Gawad Chanselor for Outstanding Senior Faculty, UP Baguio, 2006
    • Research Fellowship, University of Utah, Salt Lake City, USA, 2006 O-2007 Ap
    • Scientific Productivity Award (UP Scientist I), University of the Philippines, 2006-2008
    • Gawad Dangal ng Lipi (Agham at Teknolohiya),, Bulacan Provincial Government, 2008
    • UP Baguio Gawad Tsanselor bilang Pinakamahusay na Senior Faculty, UP (3rd time), 2008
    • Potentiano lIusorio Professorial Chair Award , UP International Publication Award (1), 2008 Jl-2009 Je
    • UCPB-MMC Professorial Award, UP International Publication Award (2), 2009 Jl- 2010Je

Research

    • Inhibition of Veratridine-evoked catecholamine release in adrenal chromaffin cells by conotoxins Mr-VIA and PIIIA [Completed]
    • Extreme divergence in gene product expressionbetween populations of species [Completed]
    • Definition of the M-Conotoxin Superfamily: Characterization of Novel Peptides from Molluscivorous Conus Venoms. [Completed]
    • Extreme Divergence in Gene Product Expression Between Populations of a Species. [Completed]
    • Biodiversity/Genetic Diversity of Selected Harmful Algal Bloom-Forming Species in the Philippines [On-going]
    • A Proteomic Approach to Elucidate the Role of Granules in Conus Venoms [On-going]
    • Bioiversity, Toxicology/Toxinology Projects [On-going]
    • Molecular Modeling of Peptides [On-going]
    • Toxicology and Toxicology of Philippine Harmful Algl Bloom Species [On-going]

Papers Presented

    • Conantokin-Pr: Specific antagonist of N-methyl D-aspartate receptor, 34th Annual Convention of the Philippine Society for Biochemistry and Molecular Biology, Philippine Rice Research Institute, Science City of Munoz, Nueva Ecija
    • D-amino acid containing peptides from Conus venoms , Seminar for faculty and students, Universidad Central del Caribe, Puerto Rico
    • The conantokin family: Conantokin-Pr is a novel sleep-inducing peptide from Conus parius, 7th Asia-Pacific Congress on Animal, Plant and Microbial Toxins, Mactan, Cebu
    • Conopeptides: the continuing frontir for world-class marine drugs, Philippine Biotechnology Venture Summit, Ateneo School of Medicine, Ortigas Ave., Pasig City
    • Research notes on Conus venom:rich source of neuropeptides, 14th Annual Convention of the Natural products Society of the Philippines, CLSU, Nueva Ecija
    • Conus venom inside out, NRCP Chemical Sciences Meeting and Scientific Session, NRCP, Bicutan, Taguig City
    • Proteomic profiling of milked venoms and venom duct contents of Conus striatus, 10th National Symposium in Marine Science
    • Conus peptides: the search for world-class therapeutic agents, PCASTRD National Symposium in Science and Technology
    • Distint families of conotoxins targeted to nicotinic acetylcholine receptors, 35th Annual Convention of the Philippine Society for Biochemistry and Molecular Biology PSMBB)

Education

    • University of the Philippines, Diliman, Quezon City, Ph.D. in Molecular Biology and Biotechnology, 1996

Publication

    • Jimenez, E.C., Olivera, B.M., Teichert, R.W. , (2007) aCConotoxin PrXA: a new family of nicotinic acetylcholine receptor antagonists
    • Biochemistry Volume 46
    • Buczek, 0., Jimenez, E.C., Yoshikami, D., Imperial, J.S., Watkins, M., Morrison, A., Olivera, B.M. , (2007 S 29) Superfamily conotoxins and prediction of single D-amino acid occurrence
    • Toxicon Volume 51
    • Teichert, R.W., Jimenez, E.C., Twede, V., Watkins, M., Hollmann, M., Bulaj, G., Olivera, B.M., (2007 O 25) Novel conantokins from Conus parius venom are specific antagonists of NMDA receptors
    • Journal of Biological Chemistry
    • Jimenez, E.C., (2007) Contryphans revisited
    • Current Topics in Peptide and Protein Research Volume 8
    • Jimenez, E.C., Olivera, B.M. , () Albanese and Other Neurotoxins
    • Translating Science Into and Pharmacology Science, Inc., Amsterdam and New York (eds)A, Atassi MZ, Dolly JO, Hallett M, Mayer N
    • Jimenez, E.C., Sasakawa, N., Kumakura, K., (2008) Effects of Sodium Channel-targeted conotoxins oncatecholaminerelease in adrenal chromaffin cells
    • Philippine Journal of Science Volume 137
    • Jimenez, E.C., (2009) Conantoxins: from sleeper activity to drug development
    • Philippine Science Letters Volume 2
    • Jimenez, E.C., (2004) Multiple 6-Bromotryptophan Residues in a Sleep-inducing Peptide
    • 43:12343-8,2004. Volume 43
    • Jimenez, E.C., (2004 N 23) Posttranslational amino acid isomerization : A functionally important D-amino acid in an excitatory peptide
    • Journal of Biological Chemistry [E-publication ahead of print]
    • Jimenez, E.C., (2004) Conus Venom Neuropeptides in Encyclopedia of Neuroscience
    • Elsevier, 3rd ed.(Adelman, G. and Smith, BH eds.)Amsterdam, the Netherlands
    • Teichert, R.W., Jimenez, E.C., Olivera, B.M., (2008) Biology and Pharmacology of Conotoxins in Botulinum Toxin: Therapeutic Clinical Practice and Science
    • Jankovic J, Albanese A, Atassi MZ, Dolly JO, Hallett M, Mayer N (eds) Amsterdam and New York: Elsevier Science, Inc, in press
    • Jimenez, E.C., (2005) Posttranslational amino acid isomerization: A functionally important D-amino acid in an excitatory peptide
    • Journal of Biological Chemistry Volume 280
    • Jimenez, E.C., (2005) Alpha S-conotoxin RVIIIA:A structurally unique conotoxin that broadly targets nicotinic acetylcholine receptors
    • Biochemistry Volume 44
    • Jimenez, E.C., (2005) Definition of D-amino-acid-containing excitatory conotoxins and redefinition of the I-conotoxin superfamily
    • FEBS Journal Volume 272
    • Jimenez, E.C., (2005) Definition of the M-conotoxin superfamily:characterization of the novel peptides from molluscivorous Conus venoms
    • Biochemistry Volume 44
    • Jimenez, E., (2003) Novel excitatory conus peptides define a new conotoxin superfamily
    • Journal of Neurochemistry Volume 85
    • Jimenez, E., (2003) Efficient folding of conotoxins and the radiation of venomous cone snails
    • Proceedings of the National Academy of Science, USA Volume 100, No. Suppl. 2

Trainings

    • Seminar for Faculty and Students, 2007, Universidad Central del Caribe,Puerto Rico-
    • 7th Asia-Pacific Congress on Animal, Plant and Microbial Toxins, 2005 O 2, Mactan, Cebu
    • NRCP Chemical Sciences Meeting and Scientific Session, 2009, NRCP, Bicutan, Taguig City
    • Philippine Biotechnology Venture Summit, Ateneo School of Medicine, 2008, Ortigas Ave., Pasig City