Scientist Profile

Photo

Leticia T. Angeles

Expertise: Pharmacology

Association

    • Philippine Pharmaceutical Association, Member
    • Philippine Association for the Advancement of Science, Member
    • Philippine Medical Association, Member
    • Manila Medical Society, Member
    • Philippine Society for Endocrinology and Metabolism, Member
    • Art Association of the Philippines, Member
    • "Big Ten" Alumni Association, Member
    • George Washington Alumni Association of the Philippines, Member
    • University of the Philippines Faculty Association, Member
    • Phi Kappa Phi (University of the Philippines Chapter), Member
    • Phi Sigma Biological Society (Alpha Chi chapter, Univ. of the Phil), Member
    • Sigma Xi (George Washington Univ. Chapter, US), Member
    • Phi Delta Gamma, Beta Chapter (National Honor Society for Graduate Women, US), Member
    • American Association of University Women, Member
    • New York Academy of Sciences, Member
    • National Society for Experimental Biology and Medicine, Member
    • Philippine Fullbright Association of the Philippines, Member
    • Who's Who in Atom, Member
    • Philippine Association for the Advancement of Research, Member
    • National Research Council of the Philippines, Member
    • Science Executive Association, Member

Employment

    • Farmacia Angeles, Pharmacist, June - Nov. 1953
    • National Research Council of the Philippines, Research Assistant, November 1953 - June 1955
    • University of the Philippines, Instructor, April 1958 - October 1961
    • College of Medicine, University of the Philippines, Assistant Professor, Oct. 1961
    • Pharmacy Graduate School, Philippine Womens' University, Professorial Lecturer, Nov. 1969 - May 1970
    • Dept. of Pediatrics, Capitol Medical Center, Chairman, June 1970
    • Philippine General Hospital, Active Consultant Staff
    • St. Luke's Medical Center, Active Consultant Staff
    • Manila Medical Center, Active Consultant Staff
    • Capitol Medical Center, Active Consultant Staff
    • UP-PGH Medical Center, Professorial Lecturer, History of Medicine
    • Western Reserve University, Clinical Demonstrator in Pediatrics, 1959 - 1960
    • National Research Council of the Philippines, Project Director, 1962
    • National Science Development Board, Project Director, 1967 - 1971
    • Philippine Journal of Pediatrics, Associate Editor, 1966
    • Philippine Journal of Science, Contributing Editor, September 1971

Award

    • Entrance College and University Scholarship, , 1951-1953
    • Metro Drug Corp. Scholaraship, Metro Drug Corp., 1951-1953
    • Phil. Pharmaceutical Association Award (Gold Medal, Cum Laude), Philippine Pharmaceutical Association , 1953
    • Research Assistantship, University of the Philippines National Research Council, 1954-1955
    • Fullbright Scholarship, Medical School, University of Wisconsin (WARF), 1955-1956
    • Fullbright Scholarship, Medical School, George Washington University (USPHS), 1956-1958
    • Teaching Fellowship, Medical School, Tulane University (USPHS), 1958-1960
    • NIH Fellowship, Woods Hole, Massachusetts Advanced Cellular Physiology, Summer 1959
    • PMA-ABBOTT Research Award (3rd prize), PMA-ABBOTT, 1962
    • Basic Research Award (1st prize), Manila Medical Society, 1962, 1965, 1967, 1969
    • Basic Research Award (3rd prize), Manila Medical Society, 1970
    • Predoctoral Fellowship, George Washington University, USPHS, Special Detail, Univ. of the Phil, 1963-1964
    • University of the Philippines Partial Fellowship, George Washington University, 1963-1964
    • NIH Fellowship in Physiology, Baylor University Medical School, Summer 1964
    • University of the Philippines Fellowship, Oak Ridge Institute of Nuclear Studies, Fall 1964
    • NRCP-NSDB Travel Grant, 10th International Cancer Congress, NRCP-NSDB, 1970

Education

    • University of the Philippines, Manila, Philippines, B. S. Pharmacy, 1953
    • University of Wisconsin, USA, B. S. Pharmacology, 1956
    • George Washington University, USA, M. S. Pharmacology, 1958
    • Tulane University, USA, Ph. D. Pharmacology, 1960
    • George Washington University, USA, Ph. D. Pharmacology, 1964

Publication

    • R. E. Parks, Jr., J. L. Way, (1956) The enzymatic basis for cellular inhibitions by purine and pyrimidine analogs
    • Intramural Symposium on Cancer Research Univ. of Wisconsin
    • R. E. Parks Jr., J. L. Way, (1957) Enzymatic mechanisms for the metabolism of purines as effected by purine analogs
    • Journal Of Pharmaceutical Experimental Therapy Volume v. 119
    • Elise Ann Brown, (March 1958) The effect of pyrimethamine on the incorporation of pyrimidine precursors into nucleic acid pyrimidines
    • Federation Proceedings Volume v. 17, No. no. 1
    • G. Robison, S. Kruger, F. W. Schueler, (1969) Effect of variation in the diet on growth of Ehrlich ascites tumor in mice
    • Archives Internationales de Pharmacodynamie et de Therapie Volume v. 126, No. nos. 1-2
    • (Oct. 1961) On the finer mechanism of antimetabolite action
    • Journal of the Philippine Pharmaceutical Association Volume v. 47, No. no. 5
    • (1961) The rationale of cancer chemotherapy
    • Surgical Bulletin Volume v. 2
    • Pilar R. T. Lim, Conrado Dayrit, (March-April 1962) Inhibition of brain cholinesterase by a new quarternary ammonium alkaloid from Phaesanthus ebracteolatus (Pres1.) Merril
    • Proceedings of the College of Medicine, UP Volume v. 1, No. no. 1
    • (Oct. - Dec. 1962) Mechanisms of action of anticancer agents
    • Philippine Journal of Cancer Volume v. 4, No. no. 4
    • (Sept. - Oct. 1962) Mechanisms of action of anticancer agents used in the therapy of leukemia
    • Proceedings of the College of Medicine, UP Volume v. 1, No. no. 4
    • (Jan. - March 1963) The basis for metabolic interference in cancer therapy
    • Acta Medica Philippina Volume v. 19, No. no. 3
    • (Jan. - Feb. 1963) Further evidence of HC-3 block of choline transport: inhibition of Ehrlich ascites tumor in mice
    • Proceedings of the College of Medicine, UP Volume v. 2, No. no. 1
    • (1963) Growth inhibitory effect of HC-3 on Ehrlich ascites tumor
    • Journal of the Manila Medical Society Volume v. 1, No. no. 3
    • F. W. Schueler, P. R. T. Lim, A. Sotto, (1964) Effect of choline deficiency on HC-3
    • Archives Internationales de Pharmacodynamie et de Therapie Volume v. 152
    • Robert P. Williams, Cora Lee Gott, (Jan. - March 1964) Effects of variation in medium on chloroquine inhibition by Serratia marcescens
    • Acta Medica Philippina Volume v. 1, No. no. 3
    • Conrado Dayrit, Ernesto V. Valdez Alicia S. Sotto, (July 1965) Studies on the mechanism of action of Phaeantharine chloride
    • Journal of the Philippine Medical Association Volume v. 41, No. no. 7
    • Conrado Dayrit, E. V. Valdez, A. Sotto, (July 1965) Studies on the possible mechanism of action of Phaeantharine (Phaeanthus ebracteolatus, Press1., Merrill). II. Effect on the incorporation of C14-labeled protein and nucleic acid precursors in bacterial systems
    • Journal of the Philippine Medical Association Volume v. 41, No. no. 7
    • A. S. Sotto, (1966) Bacterial pigment biosynthesis as affected by antimalarials
    • Journal of the Manila Medical Society Volume v. 4, No. no. 3
    • (1966) Hazards in chronic steroid therapy
    • Journal of the Manila Medical Society Volume v. 4, No. no. 5
    • (Feb. 16, 1968) Effects of a quarternary ammonium alkaloid (PTR) on insect metaporphosis
    • Paper presented at the Symposium of the Entomological Society of the Phil. Bureau of Plant Industry
    • A. Fabella, A. Gonzales, A. S. Sotto, (May-June 1968) Larvicidal action of quaternary ammonium alkaloid (PTR) on two species of mosquito
    • Journal of the Manila Medical Society Volume v. 6, No. no. 2
    • Alma Fabella, Alicia Gonzales, Alicia Sotto, (July-Sept. 1968) A possible larvicidal agent among the bisbenzyl isoquinoline alkaloids
    • Acta Medica Philippina Volume v. 5, No. no. 1
    • P. R. T. Lim, A. S. Sotto, (April 1969) Choline deficiency and HC-3 action. Possible implication in tumor induction
    • Journal of the Philippine Medical Association Volume v. 45, No. no. 4
    • J. A. Concha, B. B. Canlas, Jr., P.L. Aligaen, A. S. Sotto, (April 1969) Anti-tumor activity of Aristolochic acid isolated from Aristolochia tagala, Cham.
    • Journal of the Philippine Medical Association Volume v. 8, No. no. 1
    • Remedios A. Lapuz, Ma. Luisa E. Villarroya, (April - June 1970) Effect of Aristolochic acid on tumor membrane phospholipids
    • Acta Medica Philippina Volume v. 6, No. no. 4
    • Benjamin D. Canlas Jr., Jesus A. Concha, Alicia S. Sotto, Purita L. Aligaen, (April - June 1970) Toxicity studies on Aristolochic acid isoloated from Aristolochia tagala, Cham.
    • Acta Medica Philippina Volume v. 6, No. no. 4
    • (1971) Prolonged steroid therapy of a collagen disease with intermittent acth and antimalarial regimen
    • Fourth Asia Oceania Congress on Endocrinology
    • J. A. Concha, B. D. Canlas, (1971) Sex difference in response to a cacinostatic agent, Aristolochic acid
    • Fourth Asia and Oceania Congress on Endocrinology
    • B. D. Canlas, Jr.,, P. Sevilla-Santos, L. M. Joson, E. Javier-de Ocampo, C. T. Sales, (1971) Toxicity studies on locally-isolated actinomycins, II. Effect on the hematopoietic system of the rat
    • Journal of the Manila Medical Society Volume v. 9, No. no. 2

Trainings

    • Advanced Cellular Physiology, May 1959 - August 1959, Marine Biological Lab., Massachusetts, USA
    • Classical Physiology with Modern Instrumentation, June - July 1964, Marine Biological Lab., Massachusetts, USA
    • Bacterial Pigment Research, Aug. 1964 - Sept. 1964, College of Medicine, Baylor University, Texas, USA
    • Radioisotope Technics, Sept. 1964 - Oct. 1964, Oak Ridge Institute for Nuclear Studies, Tennessee, USA
    • 8th Pacific Science Congress on Pharmacology, Nov. 1953
    • Symposium in Cancer Research, 1956, Wisconsin, USA
    • Pan American Congress on Pharmacy and Biochemistry, 1957, Washington, DC, USA
    • FASEB (Tulane Delegate), April 1959, Atlantic City
    • Philippine Medical Association Convention, May 1962, Cebu
    • FASEB (GWU Delegate), April 1964, Chicago, USA
    • 3rd Asia and Oceania Congress on Endocrinology, Jan. 1967, Manila
    • Annual Conventions of Manila Medical Society, Manila
    • Symposium of the Entomological Society of the Philippines, Feb. 1968, BPI Manila
    • Symposium on "Recent Trends in Cancer Chemotherapy", Aug. 1969, National Institute of Science and Technology
    • Philippine Society of Endocrinology and Metabolism Annual Convention, Dec. 1970, Veterans Memorial Hospital, Q. City
    • Biota 5th Annual Convention; Symposium on "Molecular Biology", May 1970, Far Eastern University Auditorium, Manila
    • 10th International Cancer Congress, May 1970, Texas, USA
    • 4th Asia and Oceania Congress on Endocrinology, Jan. 1971 - Feb. 1971, New Zealand