Scientist Profile

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Eduardo C. Ayuste

Medicine, Outstanding Young Scientist (Clinical Surgery) (2007)

Expertise: Molecular and Cell Biology, Clinical Surgery , Basic Science Research, General and trauma surgery, Medicine

Dr. Eduardo C. Ayustre is recognized of his pioneering works and accomplishments as a scientist and an advance surgeon. His works on fluid resuscitation helped elucidate some cellular and processes in play during hemorrhagic shock. He expounded on a surgical techniques used to control presacral bleeding. He played an important role in the development a novel techniques for emergency preservation and resuscitation – suspended and (hypothermic hyperkalemic asanguinous arrest). He was instrumental in the condition of couple of Clinical Practice Guidelines for the Philippine College of Surgeons. His award-winning researches have been published internationally.

Affiliation

Clinical Associate Professor, Dept. of Surgery, UP College of Medicine, Manila

Attending Surgeon, University of the Philippines-Philippine General Hospital Medical Center, University of the Philippines, Manila

Research Instructor in Surgery, Norman M. Rich Dept. of Surgery, Uniformed Services University of the Health Sciences, Bethshesda. Maryland, USA

Association

    • Philippine Society for the Surgery of Trauma, Member
    • Philippine Association of Endoscopic Surgeons, Member
    • Philippine MedicaI Association, Member
    • Ugnayan ng Pahinungod, UP Manila, Volunteer
    • Phi Kappa Phi International Honor Society, Member
    • International Biological Honor Society, Member

Employment

    • Department of Surgery, University of the Philippines College of Medicine, University of the Philippi, , 2003 - present

Award

    • Outstanding Young Scientist (Clinical Surgery), National Academy Science and Technology-Department Of Science and Technology, 2007
    • Ben Eiseman Professorship Award in International Surgery, Department of Surgery Uniformed Services University of the Health Sciences, USA, 2004
    • International Publication Award, Philippine College of Surgeons, 2004
    • Best Undergraduate Thesis in Microbiology, Institute of Biology, College of Science, University of the Philippines Diliman, 1991
    • Best Undergraduate Paper in Cell Biology, Institute of Biology, College of Science, University of the Philippines Diliman, 1990
    • Board Topnotcher: No. 5, Board of Medicine, PRC, 1996
    • Academic Excellence Award: Class No. 6, University of the Philippines College of Medicine, 1996
    • Academic Excellence Award, Cum laude, College of Science, University of the Philippines Diliman, 1991
    • Most Outstanding High School Student, Venture Club of Lucena, Lucena City, 1987
    • Gerry Roxas Leadership Award, Gerry Roxas Foundation, 1987
    • Excellence in Science Award, Mercury Drug Corporation, 1987
    • Excellence in Mathematics Award, Mercury Drug Corporation, 1987

Research

    • Evidence-based clinical practice guidelines on the management of perioperative pain [Completed]
    • Profound hypothermia can be induced without hemorrhagic and septic complications in a swine model of vascular, splenic and colonic injuries [Completed]
    • Prospective validation of the UP-PGH practice mangement guidelines on the management of penetrating colonic injuries [Completed]
    • Gallstone Ileus: One stage repair [Completed]
    • Monoclonal antibodies against a Philippine Naegleria isolate [Completed]
    • Teaching intravenous cannulation to healthcare providers: Comparison of simulation and a traditional educaional approach [On-going]
    • Transdiaphragmatic pleural lavage in penetrating thoracoabdominal trauma [On-going]

Papers Presented

    • Profound hypothermia is superior to ultra-profound hypothermia in improving survival in a swine model of lethal hemorrage., 67th Annual Meeting of the Society of University Surgeons, San Diego, California

Education

    • Society of Apothecaries of London, Black Friars Lane, London, England, Diploma in the Medical Care of Catastrophes, 2004
    • University of the Philippines, College of Medicine, University of the Philippines Manila, , 1996
    • University of the Philippines, Diliman, Quezon City, Bachelor of Science in Biology (Cum Laude), 1991

Publication

    • Ahuja, N., Ayuste, E.C. et al., () Acetylation of cardiac histones and expression of histone regulated genes can be modulated through fluid resuscitation in a swine model of lethal hemorrhage.
    • Journal of American College of Surgeon
    • Ayuste, E.C. Alam, H.B. Chen, z. et al., (2006 Ja) Hepatic and pulmonary apoptosis following hemorrhagic shock in swine can be reduced through modifications of conventional Ringer's solution.
    • J. Trauma Volume 60(1)
    • Chen, Z. Chen, H. Rhee, P. Ayuste, E.C. et al., (2005) Induction of profound hypothermia modulates the immune response in a swine model of lethal hemorrhage.
    • Resuscitation Volume 66(2)
    • Ayste, E.C. Roxas, M.F., (2004) Validating the use of rectus muscle fragment welding to control presacral bleeding during rectal mobilization.
    • Asian Journal of Surgery Volume 27(1)
    • Ocampo, O., De la Paz, D., Ayuste, E.C., (2003) Evidence-based clinical practice guidelines on the operative management of penetrating colonic injuries.
    • Philippine Journal of Surgical Specialties Volume 58(3):
    • Alam, H.B. Rhee, P. Ayuste, E.C. et al., (2006 Ja) Does the rate of rewarming fron profound hypothermic arrest influence the outcome in a swine modle of lethal hemmorrhage.
    • Journal of Trauma Volume 60(10)
    • Alam, H.B., Chen,Z., Ahuja, N., Ayuste, E.C. et al., (2005) Profound hypothermia protects neurons and astrocytes, and preserves cognitive functions in a swine model of lethal hemorrage.a
    • Journal of Surgical Research Volume 126(2):
    • Alam, H.B. Chen,Z. Ahuja, N. Ayste, E.C. et al., (2004) Rapid induction of hypothermia improves outcome in a swine model of lethal hemorrage and complex vascular injuries.
    • Circulation (Suppl) Volume 110(17)
    • Ayuste, E.C., (2004 N) The Davao City Bombings: Implications for sisaster preparedness.
    • Dissertation for the Diploma in the Medical Cure of Catastrophes
    • Ayuste, E.., (1991) Tapey fermentation: Biochemical changes.(Most Outstanding in the Field of Microbiology)
    • Institute of Biology
    • Ayuste, E.C., (2004) Maneuver/technique used to control pre-sacral hemmorrhage-rectus muscle fragment welding.
    • Asian Journal of Surgery Volume 27(1):
    • Ayuste, E.C. et al., (2003) Evidence-based pactice management guideline.
    • Philippine Journal of Surgical Specialties Volume 58(3)
    • Ayuste, E.C. Matias, R., (1991) Monoclonal antibodies against a Philippine Naegleria isolate.
    • Natural Science Research Institue (NSRI), UP Diliman