Scientist Profile

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Alfredo C. Santos

National Scientist (1978), Academician

Expertise: Pharmaceutical Chemistry

Dr. Alfredo Santos is recognized for his research in the chemistry of natural products. He has done a lot of work in the isolation and elucidation of the phaeantharine and other alkaloids from Philippine medical plants. For 45 years, Dr. Santos served in various capacities at the University of the Philippines until he retired in 1965 as Dean of the College of Pharmacy. After his UP stint, Dr. Santos continued to do research at the UST Research Center and the National Institute of Science and Technology (NAST). In recognition of his original experimental researches in numerous alkaloids isolated from Philippine medicinal plants, Dr. Santos received Pres. Magsaysay's Distinguished Service Star in 1954. He is also recipient of the 1953 Outstanding Pharmacist Researcher of the Philippine Pharmaceutical Association and the 1973 PhilAAS Outstanding Scientist Award.

Affiliation

Dean, College of Pharmacy and Prof. of Industrial Pharmacy, UP, Manila

Association

    • National Research Council of the Phil, Member
    • Deutsche Chemische Gesellschaft, Member
    • Gesellschaft Deutsche Naturforscher und Arzte, Member
    • Society for the Advancement of Research, Member
    • Osterreisische Gesellschaft fur Microchemie, Member
    • Academico Correspondiente, Member
    • Beal Academia de Farmacia, EspaƱa, Member
    • Phil. Assoc. for the Advancement of Science, Founder Fellow
    • Colegio Medico-Farmaceuttco de Flllplnas, Inc, Member
    • Phil. Pharmaceutical Assoc, Member
    • Manila Pharmaceutical Society, Member

Employment

    • Dept. of Chemistry, Univ. of the Philippine, Asst. Instructor, 1921 - 1922
    • School of Pharmacy, Univ. of the Philippine, Asst. Instructor, 1922 - 1923
    • College of Medicine, Univ. of the Philippine, Instructor in Biochemistry, 1923 - 1924
    • School of Pharmacy, Univ. of the Philippine, Instructor In Pharmaceutical Chemistry, 1924 - 1927
    • College of Pharmacy, Univ. of the Philippine, Asst. Prof of Pharmaceutical Chemistry, 1927 - 1938
    • College of Pharmacy, Univ. of the Philippine, Assoc. Prof. and Secretary, 1938 - 1945
    • College of Pharmacy, Univ. of the Philippine, Prof. and Secretary, 1946
    • Univ. of the Philippines, Prof. of Pharmaceutical Chemistry and Secretary of the College of Pharmacy, 1952
    • Dept. of Industrial Pharmacy, Univ. of the Philippine, Prof. and Head, 1952
    • U. P. -NSDB Pharmaceutical and Pharmacological Research Project, Director, 1958/1962 - 1960/present

Award

    • Traveling Fellow , Philippine Government In Europe and United States, 1927-29
    • Anacleto del Rosario Gold Medal, Colegio Medico-Farmaceutico de Filipinas, Inc, 1931
    • Honorable mention , Anacleto del Rosario Contest , 1953
    • Distinguished Service Star , President of the Phil, 1954
    • Distinguished Alumni Award, Phil. Alumni Assoc, Ap 1957
    • Founding Member, Academy of Sciences and Humanities, N 1961

Education

    • Colegio de San Juan de Letran, Manila, A.B, 1918
    • Univ. of the Philippines, B. S. Pharm, 1923
    • Colegio de San Juan de Letran, Ph. C, 1921
    • Univ. of Santo Tomas, Pharo D, 1925
    • Westfalische Wilhelms-Universitaet, Ph. D, 1925

Publication

    • Reyes, F.R., Santos, A.C. , (1932 Ap) The Isolation of anonaine from Anona aquamosa Linnaeus
    • Phil. Journal of Science Volume 44/4
    • Santos, A.C., Valenzuela, P., (1928) Phytochemical study of Hyptis suavelens (L.) Poir
    • Journal of the Philippine Pharmaceutical Association Volume 1
    • Santos, A.C. , (1929) Beitraege zur Kenntnis der Berberisalkaloide
    • Muenster, Westfalische Vereinsdruckerei, vormals Coppenrathsche Buchdruckerei
    • Santos, A.C. , (1930) The actual status of the fermentation problem
    • Journal of the Philippine Pharmaceutical Association Volume 2
    • Santos, A.C. , (1930) Alkaloid from Anona reticulata Linnaeus
    • Journal of the Philippine Pharmaceutical Association Volume 3
    • Santos, A.C. , (1931) On the alkaloids of Archangellsia flava
    • Philippine Pharmaceutical Association Volume 3
    • Santos, A.C. , (1931) Alkaloids of Phaeanthus ebracteolatus -321
    • Journal of the Philippine Pharmaceutica1 Association Volume 3
    • Garcia, F., Santos, A.C. , (1931) Chemical and pharmaceutical studies of plumierid
    • Journal of the Philippine Pharmaceutical Association Volume 1
    • Santos, A.C. , (1931) On the alkaloids of Phaeanthus ebracteolatus
    • Journal of the Philippine Pharmaceutical Association Volume 3
    • Santos, A.C. , (1932) Alkaloids von Phaeanthus ebracteolatus
    • Berichte der Deutschen Chemischen Gesellschaft Volume 65
    • Santos, A.C., , (193) The alkaloids of Argemone mexicana
    • Journal of the Phil. Pharmaceutical Association Volume 4
    • Santos, A.C., et.al., (1932) Alkaloids on Mahonia philippinensis Takeda
    • Journal of the Phil. Pharmaceutical Association Volume 4/12
    • Santos, A.C., et.al., (1932) A contribution to the study of Luffa with special reference to Luffa cylindrica
    • Journal of the Phil. Pharmaceutical Association Volume 4
    • Santos, A.C. , (1932) On the alkaloids of Phaeanthus ebracteolatus
    • Journal of the Philippine Pharmaceutical ASsociation Volume 4
    • Santos, A.C. , (1932 Mr) Remark about anonaine
    • Philippine Journal of Science Volume 47/3
    • Santos, A.C. , (1932 O) The structure of phaeanthine
    • Natural and Applied Science Bulletin Volume 2-3/2
    • Santos, A.C., Reyes, F.R., (1932 D) Ueber Artabotrysalkaloide, I
    • Natural and Applied Science Bulletin Volume 2/4
    • Santos, A.C., et.al., (1933) Three phenolic alkaloids of Pycnarrhena manillensis
    • University of the Phil
    • Santos, A.C., et.al., (1933 D) Ambaline, a new alkaloid from Pycnarrhena manillensis
    • Natural and Applied Science Bulletin Volume 3/4
    • Sulit, J.S., Santos, A.C. , (1934) Alkaloids of Phaeanthus ebracteolatus
    • University of the Philippines
    • Santos, A.C., et.al., (1939 Jl) The alkaloids of Datura alba Nees
    • Natural and Applied Science Bulletin Volume 7/1
    • Oliveros, L.B., Santos, A.C., (1934 Mr) The alkaloid of Eurycles amboinensis
    • Natural and Applied Science Bulletin Volume 4/1
    • Samson, A.M., Santos, A.C. , (1934 O) The mercuriation of nipasol, a propyl ester of p-hydroxy benzoic acid
    • Natural and Applied Science Bulletin Volume 4/2
    • Hernandez, E., Santos, A.C. , (1935) Alkaloids of Pycnarrhena manillensis
    • University of the Philippines
    • Villanos, M.I., Santos, A.C. , (1936 D) Ambaline, a new non-phenolic alkaloid from Pycnarrhena manillensis
    • Natural and Applied Science Bulletin Volume 4/4
    • Manas-Santos, F., Santos, A.C. , (1936 Je) Macrophylline , a new alkaloid from Alstonia macrophylla Wall
    • Natural and Applied Science Bulletin Volume 5/2
    • Santos, A.C., et.al., (1937) A phytochemical stuely of Anamirsa cocculus
    • University of the Philippines Volume 32
    • Santos, A.C. , (1940) A chemical study of a mercurated carvacrol
    • American Pharmaceutical Association Volume 29
    • Mendoza-Castro, A., Santos, A.C., (1947 Ja 15) A crystalline saponin from Luffa cylindrica
    • Journal of the Phil. Pharmaceutical Association Volume 34/1
    • Santos, A.C., et.al., (1947 Ja 11) List of some Philippine medicinal plants which includes data on constituents, uses, pharmacopoeias wherein official and references
    • Journal of the Phil. Pharmaceutical Association Volume 34/1
    • Feliciano, N.M., Santos, A.C., (1947 Mr 15) The crystalline principle of Tinomiscium philippinensis Miers its identification as picrotoxin
    • Journal of the Philippine Pharmaceutical Assoc Volume 34/3
    • de la Torre, M.A., Santos, A.C., (1947 N 15) On the crystalline principle of Luna cylindrica
    • Journal of the Philippine Pharmaceutical Association Volume 34/11
    • Santos, A.C., et.al., (1948 Ja 16) Symposium on recent advances In pharmacy
    • Journal of the Phil. Pharmaceutical Association Volume 35/1
    • Santos, A.C., (1948 S 15) Table 1. Phil. medicinal plants yielding drugs of pharmacopoeial value
    • Journal of the Phil. Pharmaceutical Association Volume 35/9
    • Santos, A.C., et.al., (1949) Constituents, uses and pharmacopoeias of some Phil. medicinal plants
    • Phil. Journal of Forestry Volume 6/1
    • Santos, A.C. , (1951) Isolierung eines neues Alkaloidsalzes, Phaeantharinchlorid, aus Phaeanthus ebracteolatus
    • Archiv der Pharmazie Volume 284
    • Aguilar-Santos, G., Santos, A.C. , (1951 Jl-D) An Improved Kipp generator for the micro Dumas determination
    • Natural and Applied Science Bulletin Volume 11/3-4
    • Santos, A.C. , (1952 My) Alkaloids of Phaeanthus ebracteolatus
    • Phil. Pharmaceutical Association Volume 39/5
    • Aguilar-Santos, G., Santos, A.C. , (1952 Ap) Isolation of and preparation of several salts of Phaeantharlne, a new quaternary alkaloid of Phaeanthus ebracteolatus
    • Journal of the Phil. Pharmaceutical Association Volume 39/4
    • Santos, A.C., et.al., (1953) The chemistry and pharmacy of drugs of pharmacopoeial value from medicinal plants
    • Eighth Pacific Science Congress of the Pacific Science Association and the Fourth Far-Eastern Prehistory Congress, Abstracts of Papers
    • Santos, M.B., Santos, A.C. , (1963 Ap) The distribution of berberine and related bases in Phil. medicinal plants
    • Journal of the Philippine Pharmaceutical Association Volume 40/4
    • Santos, A.C., et.al., (1953 ) Contribution to the chemistry of alkaloids from Philippine medicinal plants
    • Proceedings of the Eighth Pacific Science Congress of the Pacific Science Association Volume 4:
    • Santos, A.C., et.al., (1954) A brief review of chemistry in schools and universitles in the Phil
    • Manila, Published by the Philippine Chamber of Industries, Inc
    • Santos, A.C., et.al., (1954) Medicinal and pharmaceutical products
    • Manila, Published by the Philippine Chamber of Industries, Inc
    • Santos, A.C., et.al., (1953) Pharmacodynamic studies on phaeantharine chloride, a new quarternary ammonium alkaloid from Phaeanthus ebracteolatus
    • Proceedings of the Eighth Pacific Science Congress of the Pacific Science Association Volume 4A
    • Santos, A.C., et.al., (1953 ) Pharmacodynamic studies on phaeantharine chloride, a new quaternaty ammonium alkaloid from Phaeanthus ebracteolatus
    • Proceedings of the Eighth Pacific Science Congress of the Phil. Science Association Volume 4A
    • Santos, A.C., et.al., (1953) Pharmacodynamic studies on phaeantharine chloride, a new quaternary ammonium alkaloid from Phaeanthus ebracteolatus
    • Proceedings of the Eighth Pacific Science Congress of the Pacific Science Association Volume 4A
    • Santos, A.C., et.al., (1955 Je 15) Proposed pharmacopoeial monographs of some Philippine drugs
    • Journal of the Philippine Pharmaceutical Association Volume 42/6
    • Santos, A.C., et.al., (1956 Ja 15) Morphological studies on Phil. drugs, I Lagerstroemia speciosa leaf, Areca catechu seed and Curcuma longa rhizome
    • Journal of the Philippine Pharmaceutical Assooiation Volume 43/1
    • Santos, A.C., et.al. , (1956 Mr 15) A study on the constituents of Tinomiscium philippinensis Diels
    • Journal of the Philippine Pharmaceutical Association Volume 43/3
    • Santos, A.C. , (1957) Bis-coclaurine alkaloids from Phaeanthus ebracteolatus
    • Proceedings of the Phytochemical Symposium, Kuala Lumpur
    • Santos, A.C., et.al., (1957) Die Konstitution des Phaeantharine
    • Archiv der Pharmazie Volume 65/5
    • Santos, A.C. , (1957) A survey of phytochemistry
    • Kuala Lumpur
    • Santos, A.C. , (1957 Mr 15) The five-year pharmacy curricula
    • Journal of the Philippine Pharmaceutical Association Volume 44/3
    • Santos, A.C., et.al., (1957 Ag 15) Morphological studies on Philippine drugs, III
    • Journal of the Phil. Pharmaceutical Association Volume 44/8

Trainings

    • 1950 Decennial United States Pharmacopoeial Convention, 1950 My, Washington, D.C
    • First International Microchemical Congress, 1950 Jl, Graz, Austria
    • Eighth Pacific Science Congress, 1953, Quezon City
    • Ninth Pacific Science Congress, 1957 N - 1957 D, Bangkok
    • Phytochemistry Symposium, 1957 D, Kuala Lumpur
    • International Union of Pure and Applied Chemistry, 1960, National Products Symposium, Australia
    • Tenth Pacific Science Congress, 1961 Ag, Honolulu
    • Phytochemistry Symposium in connection with the Golden Jubilee Celebration, 1961 S, Univ. of Hongkong