Scientist Profile

Photo

Eva Maria C. Cutiongco

Outstanding Young Scientist Award (Genetics) (200)

Expertise: Human Genetics, Cancer Genetics, Gene Therapy, Medicine, Molecular genetics, Clinical genetics, Pediatrics

Dr. Eva Maria Cutiongco-de la Paz is recognized for important part of the Phillipines-based investigative team for the Collaborative Center for XDP. Eva Maria C. Cutiongco-de la Paz, MD, FPPS, is Vice Chancellor for Research, University of Philippines Manila, Executive Director, National Institutes of Health and Program Director for Health, Philippine Genome Center, University of the Philippines. As Director of the Institute, Dr. Cutiongco-de la Paz oversees the genetic counseling and genetic testing program offered to X-linked dystonia parkinsonism (XDP) patients. This program is instrumental in the clinical care of patients, as well as ongoing research studies into the mechanism and prevalence of XDP. A recent study by Pasco et al. (2104) recently validated a new assay to detect genetic mutations found in XDP patients, which will be used at the Institute of Human Genetics. Learn more (download PDF) Dr. Cutiongco-de la Paz received her Bachelor of Science degree in biology at the UP College of Science in 1984. She finished her Doctor of Medicine degree from the UP College of Medicine in 1989, and completed her pediatric residency at the Philippine General Hospital in 1992. She received awards as an outstanding intern and most outstanding resident in pediatrics in the same institution. She had her research fellowship in molecular genetics at the International Center for Medical Research at the Kobe University Graduate School of Medicine in Japan under the Japanese Monbusho Scholarship, and took her subspecialty training in Clinical Genetics at the Hospital for Sick Children, University of Toronto, Canada as a UP Medical Alumni Society of America Scholar. She was board-certified as a fellow by the Canadian College of Medical Geneticists in 2000. Dr Cutiongco-de la Paz was a Ten Outstanding Young Men (TOYM) awardee for the field of Genetic Medicine in 2002, and was also recognized by the National Academy of Science and Technology as one of the Outstanding Young Scientists (OYS) in the same year. She was also recognized as one of the Outstanding Women in the Nation’s Service (TOWNS) for medicine in 2007. She received the 2011 UP Manila's Outstanding Researcher and the Professorial Chair for Excellence in Teaching and Research in Pediatrics and Genetics. She was the chair of the Technical Review Board of the NIH Philippines from 2006-2011, and was recently appointed as program director for the Genomics Health Program of the Philippine Genome Center. Her most recent award is the Dr. Jose Rizal Memorial Award for Research, given by the Philippine Medical Association in May of 2012.

Affiliation

Clinical Associate Professor, Department of Pediatrics, College of Medicine, Philippine General Hospital,, Manila

Research Faculty, Institute of Human Genetics, National Institutes of Health, University of the Philippines, Manila

Head, Molecular Genetics Laboratory, Institutes of Human Genetics, National Institutes of Health, University of the Philippines, Manila

Clinical Geneticist and Coordinator for Research, Philippine Newborn Screening Program

Visiting Staff, Philippine Children's Medical Center, The Medical City and Cardinal Santos Medical Center, Quezon City, mandaluyong City and San Juan, Metro Manila

Association

    • Canadian College of Medical Geneticists, Fellow
    • Philippine Pediatric Society, Diplomate
    • American Society of Human Genetics, Member

Employment

    • Dept. of Pediatrics, College of Medicine, Philippine General Hospital, Chief Resident, 1993 - 1994

Award

    • Outstanding Young Scientist Award (Genetics), National Academy Science and Technology-Department Of Science and Technology, 2002

Research

    • Low proportion of dystrophin gene deletions among Filipino duchenne and becker muscular dystrophy patients. [Completed]
    • Detection of BCR-ABL fusion in CML using flourescence in situ hybridization method [Completed]
    • Mutations of the steroid 21-hydroxylase gene among Filipino patients with congenital adrenal hyperplasia. [Completed]
    • Use of fluorescence in situ hybridization in the diagnosis of Filipino patients with Prader-Willi Syndrome and Angelman Syndrome. [Completed]
    • The clinical spectrum of Filipino patients with 22q11 deletion. [Completed]
    • Analysis of Her-2/neu gene amplification by fluorescence in situ hybridization among Filipino breast cancer patients. [Completed]

Education

    • University of the Philippines, Diliman, Quezon City, Doctor of Medicine, 1989
    • University of the Philippine, College of Science, Diliman, Quezon City, Bachelor of Science in  Biology, 1984
    • UPMASA-Roerig Fellow in Genetics, Division of Clinical Genetics, Department of General Genetics, The Hospital for Sick Children, University of Toronto, Canada, Fellowship in Clinical Genetics, 1998
    • International Center for Medical Research, Kobe University, Kobe, Japan, Research Fellowship in Molecular Genetics, 1994-1995
    • Department of Pediatrics-Philippine General Hospital, University of the Philippines, Manila, Pediatric Residency Training Program, 1990-1992

Publication

    • Padilla, C.D. Cutiongco, E.M.C. Domingo, C.F., (2001) Inherited disorders of metabolism in the newborn: A guide for primary physicians.
    • ISBN 971-91877-2-7UP Manila Office of Research, Institute of Human Genetics, National Institutes of Health
    • Cutiongco, E.M.C., (1999) Genetics and susceptibility to tuberculosis: A review
    • Frontiers in Human Genetics: Diseases and Technologies, Proceedings of the International Symposium on Human Genetics and Gene Therapy
    • Cutiongco, E.M.C., Padilla, C.P., Matsuo, M., (1995) More deletions in the 5 region than the central region of the dystrophin gene were identified in Filipino Duchenne and Becker Muscular Dystrophy patients
    • American Journal of Medical Genetics Volume 59
    • Hinek, A., Smith, A., Cutiongco, E.M.C., Gripp, K.W., Weksberg, R., (2000) Decreased elastin deposition and high proliferation of fibroblasts from costello syndrome are related to functional deficiency in the 67 KDa elastin binding protein
    • American Journal of Human Genetics Volume 66, No. 3
    • Li, M., Shuman, C., Cutiongco, E.M.C., Bender, H.A., Stevens, C., Willins-Hary, L., Day-Salvatore, D., Yong, S.L., Geraghty, M.J., Squire, J., Weksberg, R., (2001) GPC 3 mutation analysis in a spectrum of patients with overgrowth expands the phenotype of Simpson-Golabi-Behmel syndrome
    • Ameican Journal of Medical Genetics Volume 102, No. 2
    • Faustino, E.V., Cutiongco, E.M.C., (2001) Haplotype and mutation analysis in a Filipino patient with Wilson disease
    • The Philippine Journal of Pediatrics Volume 50, No. 1
    • Lee, Y.L. Padilla, C.D. Cutiongco, E.M.C. Domingo, C.F. Chua, E.L., (2000) Screening for Galactosemia
    • Philippine Journal of Pediatrics
    • Matsuda, M.L., Liede, A., Kwan, A., Mapua, C., Cutiongco, E,.M.C., Tan, A., Borg, A., Narod, S., (In Press) High prevalence of BRCA 2 mutations among unselected breast cancer
    • International Journal of Cancer
    • Cutiongco, E.M.C., (1992) Typhlitis: A necrotizing enterocolitis in leukemia
    • The PhilippineJournal of Pediatrics Volume 41, No. 3
    • Cutiongco, E.M.C., (1992) Attitudes toward home accident prevention
    • The Philippine Journal of Pediatrics Volume 41, No. 1