Scientist Profile

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Ma. Alicia M. Aguinaldo

Chemist, Outstanding Young Scientist (1993)

Expertise: Chemistry

Dr. Ma. Alicia Aguinaldo is recognized of her significant studies in the chemistry of biologically active constituents of some Philippine medicinal plants which provide scientific basis for the medicinal use of these plants identified as potential alternate drugs for therapy.

Affiliation

Associate Professor III, Research Center for Natural Sciences, Dept. of Chemistry, College of Science, University of Santo To, Espana, Manila

Association

    • Outstanding Young Scientists, Inc, Life Member
    • Natural Products Society of the Philippines, President
    • Network for the Chemistry of Biologically Important Natural Products, Member
    • National Research Council of the Philippines, Chair, Division of Chemical Sciences (X)
    • Organic Chemistry Teachers Association, Life Member
    • Philippine Association for the Advancement of Science, Life Member
    • Integrated Chemists of the Philippines, Member
    • Kapisanan ng mga Kimiko sa Pilipinas, Regular Member

Employment

    • University of Santo Tomas, Associate Profesor, 1996

Award

    • Best Poster Award (Health Sciences), National Academy Science and Technology, 1995
    • University of Santo Thomas Certificate of Recognition for Leadership in Research Activities, University of Santo Thomas, 1995
    • Plaque of Recogniton, University of Santo Thomas, 1995
    • Achievement Award for Outstanding Alumnai, University of Santo Thomas Chemistry Alumni Association, 1993
    • Dr. Jose C. Lugay Jr. Professorial Chair in Chemistry, University of Santo Thomas Graduiate School., 1993-1995
    • Outstanding Young Scientist (Chemistry), National Academy Science and Technology-Department Of Science and Technology, 1993
    • Fellow, Doctor Philosophy in Chemistry, University of the Philippines-Ateneo De Manila University-De La Salle University in Cosortium, 1984-1988

Research

    • Chemistry of selected plants with antitubercular potentials. [Completed]
    • Chemical and biological studies on Mikania cordata (Burm. F.) B.L. Robinson [Completed]
    • An antimutagenic costituent from Ixora coccinea Linn. (Rubiceae) [Completed]
    • Phytochemical sreening of selected zingiberaceae species inhibitory to mycobacterium H37RV [Completed]
    • Phytochemical to fight TB [Completed]
    • Steroids from the antitubercular fraction of the hexane extract of etlingeria elatior rhizomes [Completed]
    • Manilamine, A new 6,7-secoapparicine structure from alstonia scholaris [Completed]
    • Indole alkaloids from the antitubercular fractions of alstonia scholaris (Linn.) R. brown leaves [Completed]
    • Studies on the alkaloid extracts of the leaves of alstonia scholaris (Linn) R. brown as potential source of antituberculosis drug materials [Completed]
    • Isolation and identification of antitubercular constituents from the leaf extract of ficus nota (Blanco) Merr. [Completed]
    • Antitubercular triterpeoids from the hexane fraction of the leaf extract of ficus nota (Blanco) Merr. [Completed]
    • Antitubercular constituents from the hexane fraction of the leaf extract of ficus nota (Blanco) Merr. [Completed]
    • Bioactive saponin from the butanol extract of schefflera [On-going]
    • Isolation of constituents from the antibercular DCM extract of the leaves of alpinia purpurata (Vieill) K. schum [On-going]
    • Isolation and charaterization of the constituent fron the leavas of lunasia amara blanco (Rutaceae) [On-going]
    • Isolation and charaterization of the constituents from selected mushrooms [On-going]
    • Isolation and charaterization of the constituent fron the semipolar extract of the leaves of tectona grandis L. (Verbenaceae) [On-going]

Papers Presented

    • Artocarpus altilis (Parkins.) Fosb. as Potent~1 Source of Constituents Inhibiting the Growth of Mycobacterium tuberculosis, 21st Philippine Chemistry Congress, Ateneo de Davao University
    • Selected Zingiberaceae Species Exhibiting Inhibitory Activity against Mycobacterium tuberculosis H37Rv: A Phytochemical Profile, 4th International Symposium on the Family Zingiberaceae, Singpore Botanic Gardens
    • Bioassay-guided Isolation of Antitubercular Constituents from the Leaf Extract of Artocarpus altilis (Parkins.) Fosb, 11th Annual Convention of the Natural Products Society of the Philippines, Silliman University
    • A ~5 Highly Oxidized Cyclohexene from Uvaria rufa, 11th Annual Convention of the Natural Products Society of the Philippines, Silliman University
    • A Triterpene from the Dichloromethane Extract of Diospyros ebenaster Retz Leaves, 11th Annual Convention of the Natural Products Society of the Philippines, Silliman University
    • 248?Ethylsterols from Clerodendrum quadriloculare, Philippine Pharmaceutical Congress 2006, Thomas Aquinas Research Complex, University of Sto. Tomas, Manila, Philippines
    • Chemical Studies and Microbiological Screening of the Different Extracts of the Quezon marine Sponge, Acanthella carteri Dendy, Philippine Pharmaceutical Congress 2006, Thomas Aquinas Research Complex, University of Sto. Tomas, Manila, Philippines

Education

    • University of Santo Tomas, España, Manila, Medical Science Chemistry (Benemeritus), 1982
    • University of Santo Tomas, España, Manila, Bachelor Science Chemistry (Cum Laude), 1982
    • University of the Philippines, Diliman, Quezon City, Doctor of Philosophy in Chemistry, 1992

Publication

    • Aguinaldo, Ma. A. M. Armstrong, J., (1996) Stoechadone: A new naphthoquinone from Conospermum stoechadis.
    • Australian Journal of Chemistry Volume 49
    • Aguinaldo, Ma. A. M. Noel, M. VillaseƱor, I., (1996) Phytochemical assay for alkaloids and saponins.
    • Bioassay and Phytochemical Techniques
    • Aguinaldo, Ma. A. M. Hernandez, H. Villavicencio, H., (1995) Extraction and phytochemical screening of plants.
    • Proc., Seminar-Workshop on Bioactive Substances from Natural Sources
    • Aguinaldo, Ma. A. M. Abe, F., (1994) The germacranolides from Mikania cordata.
    • Phytochemistry Volume 38, No. (6):
    • Aguinaldo, Ma. A. M. Ocampo, O. e, (1993) Tectograndone, an anthraquinone-naphthaquinone pigment from the leaves of Tectona grandis.
    • Phytochemistry Volume 33, No. (4):
    • Aguinaldo, Ma. A. M. Almazan, L., (1992) Optimization of bonding conditions of plant phenols from Terminalia catappa Linn. to polyvinylepyrrol.
    • Acta Manilana Volume 4
    • Aguinaldo, Ma. A. M. Read, R.W., (1990) A major piperidine alkaloid from Microcos Philippinesis.
    • Phytochemistry Volume 29, No. (7):
    • Aguinaldo, Ma. A. Chua, N.M., (1988) Philippine medicinal plants active against Mycobacterium 607
    • Acta Manilana Volume 37
    • Aguinaldo, Ma. M., (1985) Spectrometric identification of phaeanthine from the leaves of Phaeanthus ebracteolatus (Pres) Merr.
    • Journal of Graduate Research Volume 15, No. (1):
    • Aguinaldo, Ma. A., (1985) Phytochemical, microbiological and pharmacological screening of medicinal plants
    • Acta Manilana
    • Aguinaldo, Ma .A. Claustro, M. Guevara, B., (1984) Alkaloid field survey in selected areas of Luzon, Philippines.
    • Acta Manilana Volume 23, No. (33):
    • Aguinaldo, Ma. A. M. Guevarra, B., (1982) Isolation of Cyanoglycoside from the outer cortex of manihot esculenta Crantz.
    • Acta Manilana Volume 21, No. (31):
    • Aguinaldo, Ma. M. Daez, C. Guevarra, B., (1978) Phytohemagglutinin in psophocarpus terragonolobus Linn.
    • Acta Manilana Volume 17, No. (27):
    • Allan Patrick G. Macabeo, Karsten Krohn, Dietmar Gehle, Scott G. Franzblau and Ma. Alicia M. Aguinaldo, (2003) Alkaloids from the Antitubercular Fraction of Alstonia Scholaris (LINN.) R. Brown Leaves
    • Transactions of the National Academy of Science and Technology Philippines Volume 25(1)
    • Dalangin, V.M. Abe, F. Yumauchi, T. Byrne, L. Franzblau, S.G. Aguinaldo, A.M., (1997) Antitubercular constituents of Lunasia amara Blanco
    • Proc., 13th Annual Philippine Chemistry Congress
    • De la Cruz, J.G. Aguinaldo, A.M. Franzblau. S. Yamauchi, T., (1997) Isolation and identification of the major constituents of Barringtonia Curanii Merr. responsive to Mycobacterium tuberculosis H37Rv.
    • Proceedings of the 13th Philippine Chemistry Congress
    • Aguinaldo, A.M. Bueno, M. Cabanilla, M. Mandap, K. Lapuz, I., (1997) The chemistry of antitubercular constituents from selected Philippine plants.
    • Proceedings of the 13th Philippine Chemistry Congress
    • Tenedor, M.U. Aguinaldo, A.M. et al., (1998) Constituents from the bioactive butanol extract of Corchorus capsularis Linn. against Mycobacterium tuberculosis H37Rv.
    • Proceedings of the 14th Philippine Chemistry Congress
    • Saludes, J.P. Franzblau S.G. Aguinaldo, A.M., (1998) Antitubercular constituents from the leaves of Morindacitrifolia Linn.
    • Proc., 14th Philippine Chemistry Congress
    • Aguinaldo, A.M., (2011 Jl 13-14) Isolation and Identification of Constituents from the Antitubercular DCM Using Skim Milk as Substrate
    • Transactions of the National Academy of Science and Technology.Abstracts of Papers Volume 33, No. 1