GOVPH

Dr. Jaime Montoya is recognized for his contribution to medicine in the field of infectious diseases, particularly for his researches on many aspects of tuberculosis; from epidemiology; molecular characterization of Philippine strain of Mycobacterium tuberculosis - a unique family of M. tuberculosis (now known as the Manila Family of M. tuberculosis), to diagnosis through immunologic tests (ELISA) utilizing different TB antigens, to the use of M. vaccae, as an innovative adjutant modality of treatment. He contributed to the preparation of the current Philippine Clinical Guidelines on the diagnosis and management of tuberculosis.

Sex: Male

Education:

• University of the Philippines Diliman, Quezon City, BS Biology, 1981
• UP College of Medicine, Manila, Doctor of Medicine, 1985
• London School of Hygiene and Tropical Medicine, University of London, United Kingdom, MS in Clinical Tropical Medicine, 1989
• University of London, -, PhD. in Immunology, 1995
• London School of Hygiene and Tropical Medicine, University of London, United Kingdom, Diplomate of the London School of Hygiene and Tropical Medicine (DLSHTM), 1999
• University of Amsterdam,, The Netherlands, Earned credit units towards an MSc in Medical Anthropology, 2005, N
• Universiteit vam Amsterdam, Netherlands, Cert of Attendance w/ paper in Gender, Reproductive & Sexual health & Fertility (5 units), 2005, D
• Universiteit van Amsterdam, Netherlands, Cert of Attendance w/ paper in Children, Health & Well-Being:A Cultural Perspective (5 units), December, 2006
• University of the Philippines, College of Medicine, Diliman, Quezon City, Currently working for an MSc in Bioethics, -
• Juntendo University School of Medicine, Tokyo, Japan, Currently a Ronpaku Fellow for a PhD

Field of Specialization:

Pulmonary tuberculosis, Medicine, Tuberculosis, Infectious Disease, Microbiology and Public Health

Researches:

Mendoza, M.T., Gonzaga, A.J., Montoya, J.C., (1997) Nature of drug resistance and predictors of multidrug-resistant tuberculosis among patients seen at the Philippine General Hospital
International Journal of Tuberculosis and Lung Diseases Volume 1, No. 1

Montoya, J.C. Reclusado, G. Somrero, L., (1997) Detection of mycobacterium tuberculosis in cerebrospinal fluid of smear-negative tuberculous meningitis using polymerase chain reaction with nested amplification.
Philippine Journal of Microbiology and Infectious Diseases Volume 26, No. 1

Montoya, J.C., (1996) Dartobicin:Tobramycin
IIMS Therapeutic Focus Volume 4

Montoya, J.C., (1996) Asia Perspective: Philippines
Medicine Digest

Montoya, J.C., (1996) Newer diagnostic tests in tuberculosis
Philippine Journal of Microbiology and Infectious Diseases Volume 25, No. 20

Montoya, J.C., Stanford, J.L., (1996) Comparison of antibody clones in cerebrospinal fluid of patients with tuberculous meningitis before and during chemotherapy using agarose gel isoelectric focusing with antigen immunoblotting
Philippine Journal of Microbiology and Infectious Diseases Volume 25, No. 2

Ditangco, R.A., Catambing, M., Gonzaga, A., Mendoza, M.T., Velmonte, M.A., Tan-Torres, T., Montoya, J.C., Ang, C.F., Roa, C. and Jorge, M., (1996) Clinical predictors of response to TB chemotherapy.
Philippine Journal of Microbiology and Infectious Diseases Volume 25, No. 1

De Groot, A. Roberts, C. Montoya, J.C., (1996) A novel algorithm for the efficient identification of T cell epitopes: Prediction and testing of candidate tuberculosis vaccine peptides in genetically diverse populations.
Vaccines

Montoya, J.C., (1995) Quinodis: Flexoxacin
TIMS Therapeutic Focus Volume 4

Posas, L. Galvex, B. Montoya, J.C., (1995) Enzyme-linked immunosorbent assay (ELISA) for rapid diagnosis of tuberculous pleural effusion using a 30,000 Dalton Native Antigen of Mycobacterium tuberculosis.
Philippine Journal of Chest Diseases Volume 3, No. 2

Montoya, J.C., (1995) Management of common Infections: Pneumonia and UTI.
Journal of the Philippine Academy of family Physicians

Schaeffler, B.A. Taylor, H.J. Montoya, J.C., (1994) Evaluation of rapid assay for detection of antibodies to Mycobacterium tuberculosis with specimens from the Philippines.
Abstracts of the 95th General Meeting of the American Society of Microbiology, Washingto DC, USA,

Montoya, J.C., Ortega, G.O., Ang, C.F., (1992) Diagnosis of tuberculous meningitis using ELISA utilizing the 30 kilodalton antigen of M. tuberculosis
Journal of the Philippine Society for Microbiology and Infectious Diseases

Montoya, J.C., (1993) Role of molecular biology in respiratory infections.
Journal of the Philippine College of Chest Physicians

Montoya, J.C. Maglonzo-de Jesus, M.S. Reclusado, G. Sombrero, I. Ang, C.F., (2001) Characterization of rifampicin resistance in Philippine isolates of mycobacterium tuberculosis utilizing the RNA polymerase b gene.
25th Anniversary and 23rd Annual Scientific Meeting (Abstracts)

Douglas, J.T., Qian, L., Montoya, J.C., Musser, J.M., Van Embden, J.D., Van Soolingen, D. and Kremer, K., (2003) Characterization of the Manila family of mycobacterium tuberculosis in Filipino patients with pulmonary tuberculosis.
Transactions of the National Academy of Science and Technology Volume 1

Maglonzo-de Jesus, M.S. Hafalla, J.C. Santiago, M.L. Montoya, J.C. Sombrero, L.T. Ramirez, B., (1997) The use of heteroduplex formation assay as a rapid tool in the detection of multi-drug resistant tuberculosis cases
The PSMID Journal

Manalo, M.F. Pineda, A.V. Montoya, J.C., (1997) Knowledge, attitudes and practices towards tuberculosis: A comparative analysis of family physicians practicing in the different regions of the Philippines.
PSMID Journal

Montoya, J.C. Dantes, R.B., (2000) The Philippine Clinical Practice Guidelines on the Diagnosis, Treatment and Control of Pulmonary Tuberculosis.
Philippine Society for Microbiology and Infectious Diseases and the Philippine College of Chest Physicians

Montoya, J.C., Mendoza, M.T., Gonzaga, A.J., Roa, C., Velmonte, M.A., Jorge, M., Tan-Torres, T., Ong, M., Barez, M.Y.C. and Ang, C.F. , (1998) Nature of drug resistance and predictors of multidrug-resistant tuberculosis among patients seen at the Philippine General Hospital, Manila, Philippines.
Int J Tuberc Lung Dis Volume 1, No. 1

Montoya, J.C., Nakamura, R.M., Velmonte, M.A., Kawajiri, K., Ang, C.F., Frias, R.A., Mendoza, M.T., Honda, I., Haga, S. and Toida, I. , (1998) MPB64 mycobacterial antigen:a new skin-test reagent through patch method for rapid diagnosis of active tuberculosis .
Int J Tuberc Lung Dis Volume 2, No. 7

Montoya, J.C., Douglas, J.T., Qian, L., Musser, J.M., Van Embden, J.D., Van Soolingen, D. an Kremer, K. , (2003) Characterization of the Manila Family of Mycobacterium tuberculosis in Filipino Patients with tuberculosis.
Journal of Clinical Microbiology Volume 41, No. 6

Montoya, J.C. , (2008) Ethical Issues and Concerns of a Clinical Investigator.
Asian Bioethics Review, Inaugural Edition

Montoya, J.C., Solon, J.A., Acosta, L., Cunanan, S., Ofori-Anyinam, O., Vinals, C., Demoitie, A., Moris, P., Janssens, M., Gatchalian, S., Bock, H., Lapierre, D. and Cohen, J. , (2009) An antigen and adjuvant system dose ranging safety and immunogenicity study of the m72 candidate tuberculosis vaccines in healthy Filipino adults. Abstract No. T3P2-07.
European Journal of Tropical Medicine and International Health. Volume 14, No. 2

Montoya, J.C. , () Sepsis: Pathophysiology and management.
Philippine Journal of Surgical Specialties Volume 52, No. 3

Montoya, J.C. , (1997) Molecular Biology: Clinical Applications in Infectious Diseases.
Philippine Journal of Microbiology and Infectious Diseases. Volume 26, No. 1

Maglonzo-de Jesus, M.S., Hafalla, J.C., Santiago, M.L., Montoya, J.C., Sombrero, L.T., Gillis, T.P. and Ramirez, B.L. , () The Rapid Detection of Rifampicin-Resistant Mycobacterium tuberculosis in the Philippines using Polymerase Chain Reaction-Heteroduplex Formation (PCR-HDF) Assay.
Philipine Journal of Microbiology and Infectious Diseases Volume 26, No. 4

Manalo, F.C., Pineda, A.V. and Montoya, J.C. , () Knowledge, Attitudes and Practices for Tuberculosis Among Filipino Family Physicians: A comparative Analysis by Practice Setting and Location. Philippine Journal of Microbiology and Infectious Diseases;27(1):6-12
Journal of Microbiology and Infectious Diseases Volume 27, No. 1

Montoya, J.C., Santiago, E., Manalo, M. and Dy, E., (1998) Clinical, radiologic and microbiologic features of drug-susceptible and resistant Mycobacterium tuberculosis and MOTT (Mycobacteria other than tuberculosis) in patients with HIV infection.
Philippine Journal of Microbiology and Infectious Diseases. Volume 27, No. 3

Montoya, J.C., Tan, F., Molina, E., Laydia, C., Manalo, F., Isaac, C. and Lazo, S. , (1999) Efficacy and Safety of an Ofloxacin Containing Regimen in the Treatment of Multi-Drug Resistant Tuberculosis.
Philippine Journal of Microbiology and Infectious Diseases Volume 28, No. 2

Montoya, J.C., Sombrero, L.T., Capeding, R.Z., Galvez, L.P., Esparar, G., Navarro, R.B. and Lagrada, M.M. , (2000) In-Vitro Susceptibility of Common Respiratory Bacterial Pathogens to Levofloxacin.
Philippine Journal of Microbiology and Infectious Diseases Volume 29, No. 1

Montoya, J.C., Orteza, G.O. and Ang, C.F. , (2000) Diagnosis of tuberculous meningitis using enzyme-linked immunosorbent assay utilizing a 30,000-dalton native antigen of Mycobacterium tuberculosis.
Philippine Journal of Microbiology and Infectious Diseases. Volume 29, No. 4

Montoya, J.C., Torres, E.G., Alora, A.T., Ordinario, A.T., Dy, E.E. and Salazar, G.C. , (2000) Diagnosis of tuberculous meningitis using ELISA utilizing the antigen A60 Mycobacterium complex: A preliminary.
Philippine Journal of Internal Medicine Volume 38, No. 5

Montoya, J.C., Berba, R., Ang, C.F. and Reclusado, G. , (2001) Evaluation of the Usefulness of AMPLICOR Polymerase Chain Reaction and Polymerase Chain Reaction with Nested Amplification in the Diagnosis of Tuberculos Meningitis.
Philippine journal of Microbiology and Infectious Diseases. Volume 30, No. 2

Mendoza, M.T., Tan-Torres, T., Catambing, M., Tiples, R.D., Montoya, J.C., Ang, C.F., Roa, C. and Gonzaga, A.J. , (2003) Clinical and in-vitro outcomes of MDRTB treatment.
Philippine Journal of Chest Diseases. Volume 10, No. 2

Bellen, A.L., Ang, C.F., Montoya, J.C. and Mendoza, M.T. , (2003) Accuracy of a bacteriophage-based assay in the rapid diagnosis of pulmonary tuberculosis.
Philippine Journal of Microbiology and Infectious Diseases Volume 32, No. 1

Canete-Mujeres, M., Montoya, J.C, Santiago, E. and Manalo, M. , (2004) Prevalence of Tuberculosis among household contacts of HIV patients with culture-confirmed pulmonary tuberculosis.
Philippine Journal of Microbiology and Infectious Diseases. Volume 33, No. 1

Montoya, J.C., Tan, F., Molina, E., Velmonte, M., Sombrero, L. and Ang, C.F. , (2006) Efficacy of Mycobacterium vaccae as an immunotherapeutic agent in the management of susceptible and multidrug-resistant pulmonary tuberculosis.
Acta Medica Philippina Volume 40, No. 2

Montoya, J.C., Maglonzo-De Jesus, M.S., Reclusado, G., Sombrero, L. and Ang, C.F. , (2007) Characterization of rifampicin resistance in Philippine isolates of Mycobacterium tuberculosis by mutation of the rpoB gene.
Philippine Journal of Science Volume 136, No. 2

Papers Presented:

• Molecular Epidemiology of Mycobacterium tuberculosis in Different populations at risk in the Philippines , Annual Meeting of the Regional Committee of the Asia and the Pacific of the International Council of Science held at the Open University of Malaysia , Kuala Lumpur, Malaysia
• An antigen and adjuvant system dose ranging safety and immunogenicity study of the m72 candidate tuberculosis vaccines in healthy Filipino adults, Joint International Tropical Medicine Meeting in Bangkok, Thailand
• Influenza Vaccine Development in the Philippines, International Round Table on Influenza Vaccination for Asia, Beijing State House, China
• An antigen and adjuvant system dose ranging safety and immunogenicity study of the m72 candidate tuberculosis vaccines in healthy Filipino adults, European Congress on Tropical Medicine and Hygiene in Verona, Italy
• Diagnosis of tuberculous meningitis using enxyme-linked immunosorbent assay utilizing the 30,000 dalton native antigen of Mycobacterium tuberculosis, 3rd Western Pacific Congress on Chemotherapy and Infectious Diseases
• Newer diagnostic tests for tuberculosis, 5th Western Pacific Congress on Chemotherapy and Infectious Diseases
• TB and HIV in Filipino patients, 4th International Congress on AIDS in Asia and the Pacific
• Detection of a novel family of tuberculosis isolates in the Philippines, 97th General Meeting of the American Society for Microbiology
• Interaction between TB and HIV; the Asia Pacific Region, 5th International Conference of AIDS in Asia and the Pacific
• Newer Diagnostic Tests for tuberculosis in children for the World Society of Pediatric Infectious Diseases, 2nd World Congress of Pediatric Infectious Diseases
• Cyclic Antibiotics in Brochiectasis, 21st International Union Against Tuberculosis and Lung Disease (IUATLD) and the 20th Philippine College of Chest Physicians Annual Convention
• Characterization of rifampicin resistance in Philippine isolates of Mycobacterium tuberculosis using the rpoB gene, International Congress of Infectious Diseases
• Efficacy of Mycobacterium vaccae as an immunotherapeutic agent in the management of drug susceptible and resistant pulmonary tuberculosis, 23rd International Congress of Chemotherapy held in Durban, South Africa
• Evaluation of Rapid Assay for Detection of Antibodies to Mycobacterium tuberculosis with specimens from the Philippines , 95th General Meeting of the American Society of Microbiology held in Washington D.C.,USA

Awards:

• Research Grant, UP Manila, 1997-1998
• Essential National Health Research Fund, , 1998
• Research Grant, Philippine Society for Microbiology and Infectious Diseases, 1997 N- 1998 D
• Dr. Elpidio Gamboa Professorial Chair in infectious Diseases, UPCM, 1997
• Research Grant, PCHRD-DOST
• 2nd Most Outstanding Research Paper Award, Philippine College of Chest Physician, 1995
• Research Grant (for two projects), Astra Foundation for Continuing Medical Research, 1994
• 2nd Most Outstanding Paper Award (Prospective Category), Dept. of Internal Medicine, UP-PGH, 1993
• Most Outstanding Research Paper Award, Philippine College of Physicians, 1993
• Outstanding Junior Research Scientist Award, Pilippine Society for Microbiology and Infectious Diseases, 1993
• Outstanding Young Scientist Award (Microbiology), NAST, 1998
• Outstanding Monograph Award (Health Sciences Division), NAST-DOST, 2004
• Recognized as one of the SARS Heroes, Johnson and Johnson Inc., 2004, Ja, 26
• Recognition for invaluable services to Phil Hospital Infection Control Society as Pres 1997-1998, Philippine Hospital Infection Control Society , 2003, D, 12
• University Entrance Scholar, University of the Philippines, Diliman, 1977
• College Scholar, University of the Philippines, Diliman, 1977, 1981
• Physicians Licensure Exam , PRC, 1986
• Passed the exam and other requirements for Career Executive Service (CES) eligibility , Career Executive Service Board, 2008
• Awarded Eligibility, Career Executive Service Board, 2009, F
• Awarded Rank of Fellow, Philippine College of Physicians, 1992
• Board Topnotcher, Philippine Specialty Board in Infectious Diseases, 1997
• Specialty Board in Tropical Medicine, Royal College of Physicians,London, U.K. [16] , 1989
• Awarded Rank of Fellow, Philippine Society of Microbiology and Infectious Diseases, 1999
• Fellow, Royal Society of Tropical Medicine and Hygiene , 1989
• Chartered Biologist, Institute of Biology, U.K. , 1989
• Infectious Disease Visiting Fellowship , University of California, Davis , 1997, S, 20-27
• Team Captain of the UP-PGH, RITM Team at the Star Wars Competition (Won First Place), PSMID, 1995, N, 27
• Holder of Elpidio Gamboa Professorial Chair in Infectious Diseases of the UP College of Medicine, UP College of Medicine, 1997 to 2003
• College Faculty Award and Plaque of Recognition (outstanding achievements in microbiology), University of the Philippines College of Medicine, 1998, Ag,
• Presidential Award for Research, Philippine Society for Microbiology and Infectious Diseases , 1998, N, 27
• Distinguished Researcher Award , Philippine College of Physicians , 2001, My, 8
• Best Scientific Poster for the Health Sciences Division, National Academy of Science and Technology, 2001, Jl
• The Outstanding Young Men of the Phils (TOYM) for 2001 in the field of Medicine/Infectious diseases, Philippine President Gloria Macapagal-Arroyo, 2001, D, 11
• Awarded a Plaque of Recognition, Imus Institute Alumni Association, 2002, Ja, 26
• Presidential Award (significant contributions as head of PSMID), Philippine College of Chest Physicians, 2002, My, 9
• Best Scientific Poster for the Health Sciences Division, National Academy of Science and Technology, 2002, Jl
• Outstanding Faculty Award in Research for the study, Philippines College of Medicine, 2002, F
• College Faculty Award and Plaque of Recognition for being one of the TOYM for Medicine, University of the Philippines College of Medicine, 2002, N
• Outstanding Book/Monograph Award , National Academy of Science and Technology, 2003, Jl, 10
• Presidential Award as President of the Philippine Society for Microbiology and Infectious Diseases, Philippine College of Physicians, 2003, My, 9
• Finalist Awardee in the PMA Centennial Essay Writing Contest, PMA, 2003, S, 28
• College Faculty Award and Plaque of Recognition , University of the Philippines College of Medicine, 2003, D
• Awarded Medal for Outstanding Achievements in Medicine as a British Council Scholar batch 1988-1989, British Ambassador, Paul Diamond, 2004, F, 11
• Outstanding Research Paper, Research Implementation and Development Office, UP Manila, 2004, Mr, 2
• Awarded an Achievement Award , Philippine Medical Association for chairing the Committee on Infectious Diseases, 2004, My, 20
• Awarded as Most Outstanding Graduate of Imus, Cavite, Carabao?s Club at the Imus Social Terrace, Imus, Cavite, 2004, Ap, 24
• First recipient of the Pfizer Foundation Philippines Research Grant in the Health Sciences , Pfizer Foundation, 2004
• First recipient of the Outstanding Research in Tropical Medicine for 2005, National Academy of Science and Technology-Lino Ed Lim Educational Development Foundation Inc, 2005, Mr, 12
• Awarded the Gen. Licerio Topacio Outstanding Achievement Award in the field of Medicine, Imuseno or citizen of Imus, Cavite, 2006, O, 3
• Outstanding Alumnus of the Jesus Good Shepherd School in the field of Medicine, Jesus Good Shepherd School, 2007, F, 11
• Manuel Luis Quezon Award For Public Service in Tuberculosis Control, Department of Health and the Philippine Coalition Against Tuberculosis, 2007, Ag, 18
• Outstanding Medical Alumni for Medical Research, UP Medical Alumni Society, 2007, D, 18
• Alumni Achievers Award, Imus Institute Alumni Association, 2008, Ja, 27
• Elected Member and awarded the title of National Academician, National Academy of Science and Technology, 2008, Jl, 10
• Awarded for Outstanding Achievements in Research, Philippine Society for Microbiology and Infectious Diseases, 2008, N, 20
• Recipient of the Dr Jose P. Rizal Memorial Awards, the first for the Research Category , Philippine Medical Association, 2010, My, 21
• Recipient of the Most Outstanding Physician Award, Philippine Medical Association, 2010, My, 21
• Recipient of the UP Alumni Association (UPAA) Distinguished Alumnus Aware for 2010, University of the Philippines, 2010, Je, 26