Allan Patrick Gose Macabeo

Details

Sex: Male

Education:

  • University of Santo Tomas, Espana Blvd., Manila 1015 Philippines, Bachelor of Science in Chemistry, 1999
  • University of Santo Tomas, Espana Blvd., Manila 1015 Philippines, Master of Science in Chemistry (Magna cum laude), 2003
  • Institut für Organische Chemie, Universität Regensburg, Universitättsstrasse 31, 93053 Regensburg, Germany, Doktor rerum naturalium (Doctor of Natural Sciences major in Organic Chemistry), (Magna cum laude), 2011

Field of Specialization:

Pharmaceutical Chemistry, Phytochemistry, Combinatorial Chemistry, Ecology, Medicinal Chemistry, Pharmacognosy, Natural Products Chemistry, Total Synthesis, Asymmetric Catalysis and Synthesis, Organic Synthesis and Catalysis

Researches:

Macabeo, A.P.G., & Lee, C.A., (2014) Sterols and triterpenes from the non-polar antitubercular fraction of Abutilon indicum
Pharmacognosy Journal Volume 6

Lirio, S., Macabeo, A.P.G., Knorn, M., Kohls, P., Wang, Y., Franzblau, S.G., & Aguinaldo, A.M., (2014) Antitubercular constituents from Premna odorata Blanco
Journal of Ethnopharmacology Volume 154

Macabeo, A.P.G., Lopez, A.D.C., Schmidt, S., Heilmann, J., Dahse, H.-M., Franzblau, S.G., & Alejandro, G.J.D., (2013) Antitubercular and cytotoxic constituents from Goniothalamus sibuyanensis
Records of Natural Products Volume 8, No. 1

Vidar, W.S., Macabeo, A.P.G., Kohls, P., Knorn, M., & Aguinaldo, A.M., (2013) Polymethoxylated flavones from Micromelum compressum
Biochemical Systematics and Ecology Volume 50

Acosta, C.J.H., Macabeo, A.P.G., & Santiago, L.A., (2013) Assessment of the antiurolithiatic and antioxidant properties of Ficus pseudopalma
Current Research in Biomedical and Pharmaceutical Sciences Volume 2, No. 2

Macabeo, A.P.G., Lehmann, C.W., & Reiser, O., (2012) Diastereoselective Synthesis of Enantiopure γ-Butenolide-butyrolactones towards Pseudopterogorgia Lactone Furanocembranoid Substructures
Cheminform Volume 23, No. 20

Macabeo, A.P.G., Tudla, F.A., Krohn, K., & Franzblau, S.G., (2012) Antitubercular activity of the semi-polar extractives of Uvaria rufa
Asian Pacific Journal of Tropical Medicine Volume 5, No. 10

Panlilio, B., Macabeo, A.P.G., Knorn, M., Kohls, P., Richomme, P., Kouam, S.F., Gehle, D., Krohn, K., Franzblau, S.G., Zhang, Q., & Aguinaldo, M.A.M., (2012) A lanostane aldehyde from Momordica charantia
Phytochemistry Letters Volume 5

Macabeo, A.P.G., Vila, J.A., Alejandro, G.J.D., Franzblau, S.G., Kouam, S.F., Hussain, H., & Krohn, K., (2012) Villarinol, a new alkenoyloxyalkenol derivative from the endemic Philippine Rubiaceae species Villaria odorata
Natural Products Communication Volume 7, No. 6

Macabeo, A.P.G., Gehle, D., Krohn, K., Franzblau, S.G., & Aguinaldo, M.A.M., (2012) Photoactivated [3+2] addition of 6,7-seco-angustilobine B to fullerene [c60]
Natural Products Communication Volume 7, No. 6

Macabeo, A.P.G., Vidar, W.S., Wan, B., Franzblau, S.G., Chen, X., Decker, M., Heilmann, J., & Aguinaldo, M.A.M., (2011) Mycobacterium tuberculosis H37Rv and cholinesterase inhibitors from Voacanga globosa
European Journal of Medicine Chemisry Volume 46

Macabeo, A.P.G., Kreuzer, A., & Reiser, O., (2011) Stereoselective routes to aryl substituted γ-butyrolactones and their application towards the synthesis of highly oxidised furanocembranoids
Organic and Biomolecular Chemistry Volume 9, No. 9

Macabeo, A.P.G., Tudla, F., Alejandro, G.J.D., Kouam, S.F., Krohn, K., & Hussain, H., (2010) Benzoylated derivatives from Uvaria rufa
Biochemical Systematics and Ecology Volume 38

Barbic, M., Macabeo, A.P.G., Kreft, S., & Hailmann, J., (2010) Astragalosides from Astragalus illyricus
Biochemical Systematics and Ecology Volume 38

Villaflores, O.B., Macabeo, A.P.G., Gehle, D., Krohn, K., Franzblau, S.G., & Aguinaldo, M.A.M., (2010) Phytoconstituents from Alpinia purpurata and their in vitro inhibitory activity against Mycobacterium tuberculosis
Pharmacognosy Magazine Volume 6, No. 24

Macabeo, A.P.G., Vilafranca, M., Aguinaldo, A.M., Krohn, K., & Hussain, H., (2008) Clerosterols from Clerodendrum quadriloculare
Biochemical Systematics and Ecology Volume 36, No. 8

Mandap, K., Marcelo, R., Macabeo, A.P.G., Franzblau, S.G., & Aguinaldo, A.M., (2007) Phenyldecanoids from the antitubercular fractions of the Philippine ginger (Zingiber officinale)
ACGC Chemical Research Communications Volume 21

Dalangin-Mallari, V., Macabeo, A.P.G., Byrne, L.T., Yamauchi, T., Abe, F., Franzblau, S.G., & Aguinaldo, M.A.M., (2007) Quinoline alkaloids from Lunasia amara inhibit Mycobacterium tuberculosis H37Rv in vitro
International Journal of Antimicrobial Agents Volume 27, No. 6

Tudla, F., Aguinaldo, M.A.M., Krohn, K., Hussain, H., & Macabeo, A.P.G., (2007) Highly oxygenated cyclohexene metabolites from Uvaria rufa
Biochemical Systematics and Ecology Volume 35, No. 1

Macabeo, A.P.G., Byrne, L.T., Franzblau, S.G., & Aguinaldo, M.A.M., (2006) 19,20E-Akuammidine from the bioactive alkaloid fraction of Alstonia scholaris leaves
ACGC Chemical Research Communications Volume 20

Macabeo, A.P.G., Krohn, K., Gehle, D., Cordell, G.A., Franzblau, S.G., & Aguinaldo, M.A.M., (2005) Indole alkaloids from the leaves of Philippine Alstonia scholaris
Phytochemistry Volume 66, No. 10

Cabuang, P.G.D., Exconde, B.S., Lim, V., Padilla, D.K.M., Salas, S.R., Lemana, B.O.C., Macabeo, A.P.G., & Alejandro, G.J.D., (2012) A novel species of Uvaria (Annonaceae) based on cpDNA markers with potential medicinal properties
Philippine Journal of Systematic Biology Volume 6

Macabeo, A.P.G., Read, R.W., Brophy, J., Cordell, G.A., Krohn, K., Gehle, D., Franzblau, S.G., & Aguinaldo, M.A.M., (2008) Activity of the extracts and indole alkaloids from Alstonia scholaris against Mycobacterium tuberculosis H37Rv
The Philippine Agricultural Scientist Volume 91, No. 3

Macabeo, A.P.G., Franzblau, S.G., Cordell, G.A., & Aguinaldo, M.A.M., (1999) A plumeran indole alkaloid from the antitubercular alkaloid extract of Catharanthus roseus (Linn.) G. Don (Apocynaceae)
Acta Manilana Volume 36, No. 51-54

Macabeo, A.P.G., Alejandro, G.J.D., Hallare, A.V., Vidar, W.S., & Villaflores, O.B., (2009) Phytochemical survey and pharmacological activities of the indole alkaloids in the genus Voacanga Thouars (Apocynaceae) - an update
Pharmacognosy Reviews Volume 3, No. 5

Macabeo, A.P.G., (2008) Synthetic uses of ClTi(Oi-Pr)3 in C-C(N) Bond Formation
Synlett Volume 20

Macabeo, A.P.G., & Aguinaldo, M.A.M., (2008) Chemical and phytomedicinal investigations in Lunasia amara
Pharmacognosy Reviews Volume 2, No. 4

Macabeo, A.P.G., Martinez, F.P., Schmidt, S., Heilmann, J., Franzblau, S.G., & Dahse, H.-M., (2013) Discovery of new antituberculosis and anticancer aromatic metabolites from the new Philippine Annonaceae species, Uvaria valderramensis
Abstracts of Papers, 245th American Chemical Society National Meeting & Exposition, New Orleans, LA, United States

Macabeo, A.P.G., Vidar, W.S., Nagle, D.G., & Mooberry, S., (2013) Biological assessment of the anticancer bisindole alkaloid globospiramine
Abstracts of Papers, 245th American Chemical Society National Meeting & Exposition, New Orleans, LA, United States

Macabeo, A.P.G., Lopez, A.D., Schmidt, S., Heilmann, J., & Alejandro, G.J.D., (2013) Phytochemical studies on the antituberculosis constituents of Goniothalamus sibuyanensis
Abstracts of Papers, 245th American Chemical Society National Meeting & Exposition, New Orleans, LA, United States

Macabeo, A.P.G., Heilman, J., Franzblau, S.G., & Reiser, O., (2013) Anticancer and antituberculosis activity of benzyloxylated benzaldehydes and 2-aryl-2-imidazolines
Abstracts of Papers, 245th American Chemical Society National Meeting & Exposition, New Orleans, LA, United States

Ali, M.T.M., Macabeo, A.P.G., Wan, B., Franzblau, S., & Reiser, O., (2013) Asymmetric approach toward new conformationally constrained cis-gamma butyrolactone
Abstracts of Papers, 245th American Chemical Society National Meeting & Exposition, New Orleans, LA, United States

Ali, M.T.M., Macabeo, A.P.G., Wan, B., Franzblau, S., & Reiser, O., (2011) Enantioselective synthesis of (-)-Geissman-Waiss lactone, antitubercular γ-butyrolactones and tetrapeptide derivatives
Abstracts of Papers, 242th American Chemical Society National Meeting & Exposition, Denver, CO, United States

Macabeo, A.P.G., Tudla, F., Paragas, E., Vidar, W., Galvez, E., Galang, Inocencio, L., Panlilio, B., Villaflores, O., Dalangin-Mallari, V., & Aguinaldo, M.A., (2010) In vitro antituberculosis activity of crude drugs and natural products from selected Philippine medicinal plants
Abstracts of Papers, Pacifichem 2010, International Chemical Congress of Pacific Basin Societies, Honolulu, HI, United States

Macabeo, A.P.G., Vidar, W.S., barbic, M., Aguinaldo, M.A.M., Franzblau, S.G., & Cordell, G.A., (2010) Globospiramine, a new antituberculosis bisaspidospermidine indole alkaloid from Voacanga globosa
Abstracts of Papers, 240th American Chemical Society National Meeting & Exposition, Boston, MA, United States

Macabeo, A.P.G., & Reiser, O., (2010) Vinylogous Mukaiyama approaches towards the stereoselective synthesis of bielschowskysin and norsecurinines
Abstracts of Papers, 240th American Chemical Society National Meeting & Exposition, Boston, MA, United States

Macabeo, A.P.G., Kreuzer, A., & Reiser, O., (2010) Diastereoselective routes to γ-aryl and γ-alkyl lactones: Mechanistic insights and model synthetic studies towards highly oxidized marine diterpenoids
Abstracts of Papers, 240th American Chemical Society National Meeting & Exposition, Boston, MA, United States

Macabeo, A.P.G., Kreuzer, A., & Reiser, O., (2011) Stereoselective Routes to Aryl Substituted γ-butyrolactones and their Application towards the Synthesis of Highly Oxidized Furanocembranoids
ChemInform Volume 42, No. 36

Macabeo, A.P.G., Krohn, K., Gehle, D., Read, R.W., Brophy, J.J., Cordell, G.A., Franzblau, S.G., & Aguinaldo, M.A.M., (2005) Indole Alkaloids from the Leaves of Philippine Alstonia scholaris
ChemInform Volume 36, No. 44

Macabeo, A.P., Vidar, W.S., Chen, X., Decker, M., Heilmann, J., Wan, B., Franzblau, S.G., Galvez, E.V., Aguinaldo, M.A., & Cordell, G.A., (2011) Mycobacterium tuberculosis and Cholinesterase Inhibitors from Voacanga globosa
ChemInform Volume 42, No. 41

Macabeo, A.P.G., Lehmann, C.W., & Reiser, O., (2013) Diastereoselective Synthesis of Enantiopure γ-Butenolide-butyrolactones towards Pseudopterogorgia Lactone Furanocembranoid Substructures
ChemInform Volume 44, No. 17

Macabeo, A.P.G., () Psychopharmacological indole alkaloids from terrestrial plants (Chapter 3)
In Kratom (Biak-Biak) and Related Compounds: the Chemistry and Pharmacology of Opioids from a Non-Opium Source. R. B. Raffa Ed. CRC Press Taylor and Francis Group.

Menguito, C.A., Albano, P.B.S., Macabeo, A.P.G., Manasala, T.L., & Santiago, K.S., (2003) Laboratory Experiments in Biochemistry
Department of Chemistry, College of Science, University of Santo Tomas, Manila

Awards:

  • Magna cum laude (M.S. Chemistry), University of Santo Tomas, 2003
  • Magna cum laude, (Doktor rerum naturalium (Doctor of Natural Sciences major in Organic Chemistry)), Institut für Organische Chemie, Universität Regensburg, 2011
  • DAAD Graduate Research Scholarship for Doctor of Science Studies (4 years), German Academic Exchange Service/Deutscher Akademischer Austauschdienst, Universitat Regensburg, 2007-2011
  • CHED-COE Scholarship for MSc Chemistry (4 years), Commission on Higher Education, 1999-2003
  • CHED-COE Scholarship for BSc Chemistry (1 year), Commission on Higher Education, 1998-1999
  • St. Martin de Porres Undergraduate Scholarship (1 year), University of Santo Tomas, 1995-1996
  • National Research Foundation (NRF)-Funded Visiting Research Fellowship (Organocatalysis), Zhao Yu Research Group, Department of Chemistry, National University of Singapore, 2012 April-June
  • DFG Research Fellowship (Short-Period), AK Reiser, Institut für Organische Chemie, Universität Regensburg, 2011 March-May
  • Conference Grant, Japan Society for the Promotion of Science (JSPS)/Department of Science and Technology, 2014 March
  • Conference Grant, International Union of Pure and Applied Chemistry (IUPAC) and Asian CORE, 2013 November
  • Individual Research Grant, International Foundation for Science (IFS) (Stockholm, Sweden), 2013 June
  • Large-Equipment Grant, The German Academic Exchange Service (DAAD)/German Federal Economics Ministry (BMZ), 2013 May
  • Small-Equipment Grant, The German Academic Exchange Service (DAAD), 2011 April
  • Young Scholars Award, Merck Inc. and Chemical Societies of the Pacific Basin, PACIFICHEM, 2010
  • Freunde der Universität Regensburg Travel Award (Regensburg, Germany), Universität Regensburg, 2010 August
  • International Union of Pure and Applied Chemistry (IUPAC) Travel Award (Brisbane, Australia), International Union of Pure and Applied Chemistry (IUPAC), 2001 June
  • Third Prize (Best Poster), 62nd Annual Convention of the Philippine Association for the Advancement of Science (PhilAAS), Philippine Association for the Advancement of Science (PhilAAS), 2013 September
  • Awardee (Third Prize), National Academy of Science and Technology (NAST) Talent Search for Young Scientists, National Academy of Science and Technology (NAST), 2013 July
  • Individual Research Grant, Philippine Council for Health Research and Development (PCHRD), 2013 June
  • The Merck Young Scientist Award (MYSA) in the Health Sciences – Philippines, Merck Inc., 2013 May
  • Travel / Conference Grant, Commission for Higher Education (CHED), 2013 April
  • First Prize, Poster Competition, 3rd Metro Manila Health Research and Development (MMHRDC), 2012 February
  • Third Prize, Poster Competition, 3rd Metro Manila Health Research and Development (MMHRDC), 2012 February
  • Best Research Paper, Gruppo Medica Award for Outstanding Undergraduate Research in Herbal Medicine (with undergraduate student, Warren S. Vidar), Gruppo Medica, Inc. and the Philippine Council for Health Research and Development, 2007 August
  • Best Scientific Paper, 11th Annual Convention of the Natural Products Society of the Philippines, Natural Products Society of the Philippines, 2006 December 4-5
  • Third Best Research Paper, Gruppo Medica Award for Outstanding Undergraduate Research in Herbal Medicine, Gruppo Medica, Inc. and the Philippine Council for Health Research and Development, 1999
  • Finalist in the Chemical Division, Scientific Research Poster Competition of the 5th Annual Meeting of the National Research Council of the Philippines, National Research Council of the Philippines, 2007
  • Finalist, 14th Scientific Poster Competition for Health and Related Technologies, Philippine Council for Health Research and Development, 2003 July
  • Finalist, Gruppo Medica Award for Outstanding Undergraduate Research in Herbal Medicine (with undergraduate students, Florie A. Tudla and Erickson M. Paragas), Gruppo Medica, Inc. and the Philippine Council for Health Research and Development, 2005 July
  • Finalist, 2005 DOST PCASTRD Outstanding Thesis and Dissertation in the Advanced Science and Technology Sector - Indole alkaloids from the leaves of Alstonia scholaris (L.) R. Br., photoinduced synthesis of 6,7-seco-angustilobine B-fullerene[C60] adduct, DOST-PCASTRD, 2005 November
  • Dangal ng UST San Alberto Magno Award as Outstanding Researcher in Science and Technology, University of Santo Tomas, 2014 March
  • Dangal ng UST San Lorenzo Award for Outstanding National Achievement, University of Santo Tomas, 2014 March
  • Travel Grant from the UST Office for Grants and Endowment (OGE), University of Santo Tomas, 2013 April
  • Dangal ng UST San Alberto Magno Award for Best Published Paper in Science and Technology, University of Santo Tomas, 2013 March
  • The 2012 UST Biennial University Research Award Ceremonies for International Publications Award, University of Santo Tomas, 2012 September
  • The 2010 UST Biennial University Research Award Ceremonies for International Publications Award, University of Santo Tomas, 2010 July
  • The 2008 UST Biennial University Research Award Ceremonies for International Publications Award, University of Santo Tomas, 2008 November