Sex: Male
Education:
- University of the Philippines, Diliman, Quezon City 1101, Bachelor of Science in Chemistry with research in Natural Products Chemistry, 2001 April 21
- The University of North Carolina at Greensboro, Department of Chemistry and Biochemistry, Patricia A. Sullivan Science Building, Greensboro, NC 27402-6170; PO Box 26170,
- Doctor of Philosophy in Medicinal Biochemistry with concentration in Mass Spectrometry and Natural Products Chemistry, 2011 December 15
Field of Specialization:
Mass Spectrometry, Microbiology, Medicinal Biochemistry, Assay (Metabolite Profiling) Development
Researches:
Junio, H.A., Sy-Cordero, A.A., Etterfagh, K.A., Burns, J.T., Micko, K.T., Graf, T.N., Richter, S.J., Cannon, R.E., Oberlies, N.H., & Cech, N.B., (2011) Synergy-directed fractionation of botanical medicines: a case study with goldenseal (Hydrastis canadensis)
Journal of Natural Products Volume 74, No. 7
Ettefagh, K.A., Burns, J.T., Junio, H.A., Kaatz, G.W., & Cech, N.B., (2011) Goldenseal (Hydrastis canadensis L.) extracts synergistically enhance the antibacterial activity of berberine via efflux pump inhibition
Planta Medica Volume 77, No. 8
Cech, N.B., Junio, H.A., Ackermann, L.W., Kavanaugh, J.S., & Horswill, A.R., (2012) Quorum quenching and antimicrobial activity of goldenseal (Hydrastis canadensis) against methicillin-resistant Staphylococcus aureus (MRSA)
Planta Medica Volume 78
Junio, H.A., Todd, D.A., Etterfagh, K.A., Ehrmann, B.M., Kavanaugh, J.S., Horswill, A.R., & Cech, N.B., (2013) Quantitative analysis of autoinducing peptide I (AIP-I) from Staphylococcus aureus cultures using ultrahigh performance liquid chromatography–high resolving power mass spectrometry (UPLC-HRMS)
Journal of Chromatography B Volume 930
Bame, J.R., Graf, T.N., Junio, H.A., Bussey III, R.O., Jarmusch, S.A., El-Elimat, T., Falkinham III, J.O., Oberlies, N.H., Cech, R.A., & Cech, N.B., (2013) Sarothrin from Alkanna orientalis is an antimicrobial agent and efflux pump inhibitor
Planta Medica Volume 79
Ettefagh, K.A., Todd, D.A., Junio, H.A., Horswill, A.R., & Cech, N.B., (2012) Mass spectrometric detection of virulence factors from methecillin-resistant Staphylococcus aureus (MRSA)
Planta Medica Volume 78, No. 11
Cech, N.B., Junio, H.A., Tarney, K.M., Cannon, R.E., Graf, T.N., & Oberlies, N.H., (2008) A role for non-alkaloidal constitutes in the antibacterial activity of Hydrastis canadensis
Planta Medica Volume 74, No. 9
Papers Presented:
- Synergy Directed Fractionation: A Modified Approach to Bioassay-Guided Isolation from Goldenseal (Hydrastis canadensis, L.), The 52nd Annual Meeting of the American Society of Pharmacognosy. San Diego, CA
- A Flavonoid from Goldenseal (Hydrastis canadensis, L.) Synergistically Enhances the Antibacterial Activity of its Major Alkaloid Berberine, 2010 Joint Annual Meeting of the American Society of Pharmacognosy & the Phytochemical Society of North America. St Petersburg Beach, FL
- Non-Alkaloidal Compounds from Goldenseal (Hydrastis canadensis, L.) Synergize the Antibacterial Activity of Known Alkaloidal Constituents, The 50th Annual Meeting of the American Society of Pharmacognosy. Honolulu, HI
- Plant Box Diversity: Ednophytes from Common Plants Synthesize Novel Small Molecules, Next Generation Scientist Research Day, Basel, Switzerland