Sex: Male
Education:
- Auckland University, Auckland, New Zealand, Doctor of Philosophy in Pathology and Molecular Medicine, 2005
- University of the Philippines, Manila, MS in Biochemistry, 1999
- Far Eastern University, Manila, Philippines, BS Chemistry, 1991
Field of Specialization:
Mechanical Engineering, Robotics, Mechatronics, Instrumentation and Controls
Researches:
Chung, F., Liu, J., Ching, L.M., Baguley, B.C., (2007 My1 [Epub ahead) Consequences of incresed vascular permeability induced by treatment of mice with 5,6-dimethylxanthenone-4-acetic acid DMXAA) and the thalidomide
Cancer Chemotherapy and Pharmacology
Endres, C.J., Hsiao, P., Chung, F., Unadkat, J.D., (2006 Ap 27) The role of transporters in drug interactions
European Journal of Pharmaceutical Sciences Volume 27, No. 5
Chung, F., () PET Imaging of Inhibition of P-Glycoprotein (P-gp)Activity of the Blood-Placental and Blood-Brain Barrier in the Pregnant Afacaca nemestrina: An OPRU Study
Manuscript in Preparation
Chung, F., () Simultaneous PET Imaging of P-glycoprotein Inhibition in Multiple Tissuesf the Pregnant nonhuman Primate
Manuscript in Preparation
Chung, F., Lu, J., Palmer, B.D., Kestell, P., Browett, P., Baguley, B.C., Tingle, M., Ching, L.M., (2004 S) Thalidomide Pharmacokenetics and Metabolite Formation in Mice, Rabbits and Multiple Myeloma Patients
Clinical Cancer Research Volume 10, No. 17
Chung, F., Wang, L.C., Kestell, P., Baguley, B.C., Ching, L.M., (2003) Modulation of Thalidomide Pharmacokenetics by Cyclophosphamide or 5,6-Dimethylxanthenone-4 Acetic Acid (DMXAA)in Mice: The Role of Tumor Necrosis Factor
Cancer Chemotherapy and Pharmacology Volume 14
Chung, F., Palmer, B.D., Muller, G.W., Man, H.W., Kestell, P., Baguley, B.C., Ching, L.M., (2003) Effect of 3-Fluorothalidomide and 3-Methylthalidomide Enentiomers on Tumour Mecrosis FactorProduction and Antitumur Resposes to the AntivascularAgent 5,6-Dimethylxanthenone-4-Acetic Acid (DMXAAA)
Oncology Research Volume 14
Chung, F., () Rapid Solid Phase Extraction Method to Quantity {" C} Verapamil-Metabolites in Human and Macaque Plasma
In Press
Chung, F., (2006) PET Imaging of Inhibition of P-glycoprotein (P-gp)activity at the Blood Placental and Blood-Brain Barrier in the Pregnant Macaca Nemestrima: An OPRU Study
The AAAPS Journal Abstract R6078 Volume 8, No. 82
Chung, F., (2006) Intra and Inter-individual Variability in Lymphocyte P-glycoprotein (P-gp) Activity and Expression as Measured by Fluorescent Activated Cell Sorter
The AAAD Journal Abstract 5133
Chung, F., Eyal, S., Muzi, M., Link, J.M., Mankoff, D.A., Kaddoumi, A., O'Sullivan, F., Hsiao, P., Unadkat, J.D., (2010 Ja) Pregnancy Does Not Increase CYP3A or P-Glycoprotein Activity in the Non-Human Primate
British Journal of Pharmacology
Chung, F., Eyal, S., Muzi M., Link, J.M., Mankoff, D.A., Kaddoumi, A., OâSullivan, F., (2009 My) Simultaneous PET imaging of P-glycoprotein Inhibition in Multiples Tissues of the Pregnant
Journal of Nuclear Medicine
Chung, F., Zhang, H., Wu, X., Naraharisetti, S.B., (2009 My) Pregnancy Does Not Increase CYP3A or P-Glycoprotein Activity in the Non-Human Primate,
The Journal of Pharmacology and Experimental Therapeutics
Chung, F., Zhang, H., Wu, X., Naraharisetti, S.B., Whittington, D., Mirfazaelian, A., (2009 Mr) As in humans, pregnancy increases the clearance of the protease inhibitor, nelfinavir
The Journal of Pharmacology and Experimental Therapeutics
Chung, F., Unadkat, J.D., Sasongko, L., Whittington, D., Eyal, S., Mankoff, D., Collie, A.C., (2008 N) Rapid solid-phase extraction method to quantify [11C]-verapamil, and its [11C]-metabolites, in human and macaque plasma
Nuclear Medicine and Biology
Chung, F., Liu, J., Ching, L.M., Baguley, B.C., (2008) Consequences of increased vascular permeability induced by treatment of mice with
Cancer Chemotherary and Pharmacology
Francisco Chung, Endres CJ, Hsiao P, Chung F, Unadkat JD, (2006 Ap) The role of transporters in drug interactions
European Journal of Pharmaceutical Sciences
Chung, F., Lu, J., Palmer B.D., Kestell P., Browett P., Baguley, B.C., Ching, T.M., (2004 S) Thalidomide pharmacokinetics and metabolite formation in mice, rabbits and multiple myeloma patients
Clinical Cancer Research
Chung, F., Wang, L.C., Kestell, P., Baguley, B.C., Ching, L.M., (2004 My) Modulation of thalidomide pharmacokinetics by cyclophosphamide or 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in mice: the role of tumour necrosis factor
Cancer Chemotherapy and Pharmacology
Chung, F., Palmer, B.D., Muller, G.W., Man, H.W., Kestell, P., Baguley, B.C., Ching, L.M., (2003) Effect of 3-fluorothalidomide and 3-methylthalidomide Enantiomers on tumour necrosis factor production and antitumor responses to the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA).
Oncology Research
Papers Presented:
- PET Imaging of Inhibition of P-glycoprotein (P-gp)activity at the Blood Placental and Blood-Brain Barrier in the Pregnant Macaca Nemestrima: An OPRU Study, American Association of Pharmaceutical Scientist, San Antonio, Texas, USA
- Pharmacokenetics studies of Thalidomide in Mice, Rabbits, and MUltiple Myeloma Patients, Australian Society for Clinical Exprimental Pharmacologists and Toxicologists (ASCEPT) Annual Meeting, Sydney, Australia
- Intra and Inter-individual Variability in Lymphocyte P-glycoprotein (P-gp) Activity and Expression as Measured by Fluorescent Activated Cell Sorter, American Association of Pharmaceutical Scientist, San Antonio, Texas, USA
- Altered Pharmacokinetics of Thalidomide in Combination Therapy with Cyclophosphamide or DMXAA Role of TNF, New Zealand Society for Oncology Annual Scientific Meeting, Aukland, New Zealand
Awards:
- Balik Scientist Award, DOST, 2009
- PhD Early Completion Award, The University of Aukland, 2004
- Post Graduate Programme, Asian Development Bank (ADB), 2001-2004
- Research Fellowship, Lung Cancer of the Philippines, 1998
- Thesis Grant, PCHRD-DOST
- Travel Fellowship, Maurice and Phyllis Paykel Trust, 2003