Researches:
Leff AR,. Muñoz NM., Shoulberg N., (1982) Alpha-adrenergic contractile properties of canine tracheal muscle in vitro
Fed.Proc
Leff, A.R., Muñoz, N.M., (1981) Alpha-receptor subtypes causing tracheal muscle contraction
Clinical Research
Myou, S., Zhu, X., Myo, S., Boetticher, E., Meliton, A., Liu, J., Lambertino, A., Muñoz, N.M., Leff, A.R., (2003) Activation of group IV cystolic PLA2 in human eosinophils by phosphoinositide 3-kinase through mitogen activated protein kinase-independent pathway
Journal of Immunology
Muñoz, N.M., Meliton, A.Y., Meliton, L.N., Dudek, S.M., Leff, A.R., (2009) Secretory gVPLA group V Phospholipase A2, regulates actue lung injury and neutrophilic inflammation caused by LPS in mice
American Journal of Physiology: Lung Cell Molecular Physiology
Muñoz, N.M.,Kim, Y.J., Meliton, A.Y., Lambertino, A., Kim, K.P., Han, S.-K., Boetticher, E., O'Leary E., Myou, S., Zhu, X., Bonventure, J., Leff, A.R., (2003) Human group IVA phospholipase A2-independent cysteinyl leukotriene synthesis in eosinophils
Journal of Biological Chemistry
Myou S., Zhu X., Boetticher E., Qin Y., Meliton A., Lambertino A., Muñoz NM.,Hamann KJ.,Leff AR, (2002) Regulation of adhesion of AML14-3D10 cells by surface clustering of B2-integrin caused by ERK-independent activation of cPLA2
Immunology
Schmidt, D.T., Dent, G., Ruhmann, Muñoz, N.M., Leff, A.R., Rabe, K.F., (2002) Studying human airway pharmacology in microsections:applications of videomicrometry
Eurupean Respiratory Journal
Muñoz, N.M., Boetticher, E., Sperling, A., Kim, K-P., Meliton, A.Y., Zhu, X., Lambetino, A., Cho, W., Leff, A.R., (2002) Quantitation of secretory group V phospholipase A2 in human tissues by sandwich enzyme linked immunoassay
Journal of Immunological Methods
Meliton, A.,,Muñoz, N.M.,Meliton, LN., Binder, D., Osan, C.M., Zhu, X., Dudek, S., Leff, A.R., (2010) Cytosolic group IVa phospolipase A2 mediates IL-8/cxcl8-induced transmigration of human polymorphonuclear
Journal of Inflammation Volume 7, No. 14
Dudek, S.M., Muñoz, N.M., Desai, A., Osan, C.M., Meliton, A., Leff, A.R., (2010 My 6) Group V phospholipase A2 mediates barrier discruption of human pulmonary endothelial cells caused by LPS in vitro
American Journal of Respiratory Cell and Molecular Biology
Meliton, A.,Muñoz, N.M.,Osan, C.M., Meliton, L.N., Leff, A.R., (2009) Leukotriene D4 activates B2-integrin adhesion in human polymorophonuclear leukocytes
European Respiratory Journal
Meliton, A.Y., Muñoz, N.M., Leff,A.R., (2008) Attenuated translocation of gIVaPLA2 and annexin-1 synthesis prevents glucocorticoid-induced blockade of B2-integrin adhesion
Journal of Leukocyte Biology
Myou, S., Zhu, X., Myo, S., Boetticher, E., Meliton, A.Y., Liu, J., Muñoz, N.M., Leff, A.R., (2003) Blockade of airway inflammation and hyperresponsiveness by IIIV-TAT-dominant negative Ras
Journal of Immunology
Meliton, A.Y., Muñoz, N.M., Leff, A.R., (2007) Blockade of Avidity and Focal Clustering of B2-integrin by Cysteinyl Leukotriene Antagonism Attenuates Eosinophil Adhesion
Journal of Allergy and Clinical Immunology
Muñoz, N.M.,Meliton, A.Y.,Zhu, X., Leff, A.R., (2007) Attenuates cell migration and airway hyperresponsiveness in sensitized mice
Journal of Immunology
Zhu, X., Learoyd, J., Butt, S., Zhu, L., Usatyuk, P.V., Natarajan, V., Muñoz,NM.,Leff, A.R., (2007) Regulation of Eosinophil Adhesion by Lysophosphatidylcholine via a Non-store Operated Ca2+ Channel
American Journal of Respiratory and Critical Care Medicine
Meliton, A., Muñoz, N.M., Lambertino, A., Boetticher, E., Learoyd, J., Zhu, X., Leff, A.R., (2006) PDE-4 inhibition on B2-integrin adhesion caused by LTB4 and TNFa in human neutrophils
Eurupean Respiratory Journal
Muñoz, N.M., Meliton, A., Lambertino, M., Boetticher, E., Learoyd, J., Sultan, F., Zhu, X., Cho, W., Leff, A.R., (2006) Transcellular secretion of group V phospholipase A2 from the epithelium induces B2-integrin mediated adhesion and synthesis of LTC4
Journal of Immunology
Zhu, X., Sano, H., Kim, K.-P., Sano, A., Boetticher, E.E., Muñoz, N.M., Cho, W., Leff, A.R., (2001) Role of MAP-kinase-mediated phosphorylation on cytosolic phospolipase PLA2 in arachidonic acid metabolism in human eosinophil
Journal of Immunological Methods
Myou, S., Leff, A.R., Myo, S., Boetticher, E., Tong, J., Meliton, A.Y., Liu, J., Muñoz, N.M., Zhu, X., (2003) Blockade of inflammation and airway hyperresponsiveness in immune-sensitized mice by dominant-negative phosphoinosotide 3-kinase-TAT
Journal of Experimental Medicine
Leff Ar., Muñoz NM.,Tallet J., Cavigelli M., David A., Garrity ER, (1984) Autonomic response characteristics of porcine airways in situ
Am.Rev.Respir.Dis
Leff Ar., Muñoz NM., Garrity ER., Stimler N., Tallet A., (1983) Autonomic modulation of immune degranulation response in canine respiratory airways
Clin.Res
Leff Ar., Muñoz NM.,Tallet J., Cavigelli M., David A., Garrity ER, (1984) Augmentation of parasympathetic contraction in tracheal and bronchial smooth muscle by prostaglandin F2x in situ
Am.Rev.Respir.Dis
Leff Ar., Muñoz NM., Popovich KJ.,Sheldon G., Mack MM., Denberg P., Blake J., White SR, (1987) Role of platelets in contraction of canine trachealis muscle elicited by platelet activation factor in vivo
Am.Rev.Respir
Leff Ar., Muñoz NM., Weisner R., Panetierri R., Zak R, (1991) Maturational expression of myosin heavy chain mRNA in swine trachealis muscle
Am.Rev.Respir.Dis
Leff, A.R., Muñoz, N.M., Guest, K., Ikeda, K., Seow, Y., Mitchelle, R.W., (1991) Post-ganglionic activation and contractile characteristics of neonatal swine tracheal smooth muscle
American Review of Respiratory Disease
Leff, .R., Muñoz, N.M., Ikeda, K., Guest, K., Murphy, T.M., Seow, C.Y., Halayko, A.,Stephens, N.L., Mitchelle, R.W., (1991) Correlation of contractility, myosin isoform expression and maturation in porcine tracheal muscle
American Review of Respiratory Disease
Myou, S., Zhu, X., Boetticher, E., Myo, S., Meliton, A., Lambertino, A., Muñoz, N.M., Leff, A.R., (2002) Blockade of focal clustering and active conformation of B2-integrin-mediated adhesion of eosinophils to ICAM-1 caused by transduction of HIV TAT-dominant negative Ras
Journal of Immunology
Leff Ar., Muñoz NM.,Garrity ER., Stimler N., Fried R., (1983) Selective degranulation of canine third order bronchus by compound 48/80 and Ascaris suum antigen in situ
Am.Rev.Respir.Dis
Sano, M., Leff, A.R., Myou, S., Boetticher, E., Meliton, A.Y., Learoyd, J., Lambertino, A,T.,Muñoz, N.M., Zhu, X, (2005) Regulation of interleukin-5-induced beta2-integrin adhesion of human eosinophils by phosphoinositide 3-kinase
American Journal of Respiratory and Cell Molecular Biology
Liu, J., Zhu, X., Myo, S., Lambertino, A.T., Xu, C., Boetticher, E., Muñoz, N.M., Sano, M., Condoba, M., Learoyd, J., Meliton, A., Leff, A.R., (2005) Fluricasone propionate inhibits B2-integrin mediated eosinophil adhesion via increased annexin-1 expression
Journal of Allergy and Clinical Immunology
Myo, S., Zhu, X., Myou, S., Meliton, A,Y., Boetticher, E., Lambertino, A.T., Xu, C., Muñoz, N.M.,Leff, A.R., (2004) Additive inhibition of fluticasone propionate (FP) and salmeterol on B3-integrin-mediated adhesion to human eosinophils
European Respiratory Journal
Liu, J., Muñoz, N.M., Meliton, A.Y., Zhu, X., Lambertino, A., Xu, C., Myo, S., Myou, S., Boetticher, E., Johnson, M., Leff, A.R., (2004) B2-integrin adhesion caused by eotaxin but not IL-5 is blocked by PDE-4 inhibition and B2-adrenoceptor activation in human eosinophils
Pulmonary Pharmacology and Therapeutics
Leff AR,. Muñoz NM, (1981) Selective autonomic stimulation of canine tracheal muscle with 1,1-dimethyl1-4-phenylpiperazinium iodide (DMPPP)
Am.Rev.Respir.Dis
Sano, H., Zhu, X., Sano, A., Boetticher, E.E., Shioya, T., Muñoz, N.M., Leff, A.R., (2001) ERK1/2-mediated phosphorylation of cPLA2 is essential for human eosinophil adhesion to fibronectin
Journal of Immunology
Sano, A., Zhu, X.,Sano, H.,Muñoz, N.M., Boetticher E., Leff, A.R., (2001) Regulation of eosinophil function by phosphatidylinositol-specific PLC and cytosolic PLA2
American Journal of Physiology:Lung Cell Molecular Physiology
Myou, S., Sano, H., Fujimura, M., Zhu, X., Kurashima, K., Kita, T., Nakao, S., Nonomura A., Kim, K.P., Shioya, T., Muñoz, N.M.,Cho, W., Leff, A.R., (2001) Blockade of eosinophil migration and airway hypersponsiveness by sPLA2-inhibition
Natural Immunology
Zhu, X., Lambertino, A., Haughton, T., McGilvira, J.D., Chang, X., Rawall, V.H., Muñoz, N.M.,Leff, A.R., (2003) Structural determinants of blockade of eosinophil activation, adhesion, and secretion by synthetic analogs of phomactin
Life Science
Meliton, A., Muñoz, N.M., Liu, J., Lambertino, A., Boetticher, E., Myo, S., Myou, S., Zhu, X., Johnson, M., Leff, A.R., (2003) Blockade of LTC4 synthesis by additive inhibition of gIV-PLA2 phosphorylation: Effect of salmeterol and PDE4 inhibition in human eosinophils
Journal of Allergy and Clinical Immunology
Kim, Y.S., Kim,K.-P., Han, S.K., Muñoz, N.M., Zhu X., Sano, H., Leff, A.R., Cho, W., (2002) Group V phospholipase A2 induces leukotriene synthesis in human neutrophils through activation of group IVa PLA2
Journal of Biological Chemistry
Leff Ar., Muñoz NM.,Murphy TM., Hirshman C., Blake J.,, (1987) Mechanism of airway hypercontractility in Basenji-Greyhound dogs
Am.Rev.Respir.Dis
Leff Ar., Muñoz NM.,Guest K., Kirchoff C., Popovich K, (1990) Tritiated quinuclidinyl benzilate binding in airway generations of maturing swine
FASEB J
Leff Ar., Muñoz NM., Tutins C, (1989) Bronchoconstriction elicited by platelet activating factor (PAf) in isolated airways perfused with platelet-free solution
Physiologist
Leff Ar., Muñoz NM.,Roy LM., Murphy TM., Mack M., Kelly EA, (1989) Distribution of airway contractile responses within the central airways of swine: effect of maturation
Am.Rev.Respir
Leff Ar., Muñoz NM.,Solway J., Hernandez C., Tutins C., Stimler-Gerard N., Eappen S., Alger L., Ray DW, (1989) Secretory cell mediator release during hypernea-induced bronchoconstriction in guinea pigs
Am.Rev.Respir.Dis
Leff Ar., Muñoz NM., Murphy TM., Roy L., Mitchelle RW., Kelly E, (1989) Effect of maturation of topographical distribution of isometric force generation in major bronchoconstriction in guinea pigs
Am.Rev.Respir.Dis
Leff, A.R., Muñoz, N.M., White, S.R., Ohno, S., Blake, J., Gleich, G.J., (1989) Spontaneous contractions and mechanism of epithelial activation in augmented contractility of tracheal smooth muscle elicited by eosinophil major basic protein (MBP) in guinea pig in vivo
Am.Rev.Respir.Dis
Leff Ar., Muñoz NM.,Strek ME., Gerard NP., Blake J., Tutins C., Kelly E, (1989) Quantitation and topographical localization of mast cell secretion of histamine during antigen challenge in isolated-perfused rat lung
Am.Rev.Respir.Dis
Leff Ar., Muñoz NM., Brofman JD., White SR., Blake JS., Tutins C, (1989) Differential sympathetic neural activation elicited by respiratory and metabolic acidosis
Am.Rev.Respir.Dis
Leff, A.R., Muñoz, N.M., Shioya, T., (1988) Comparative distribution of muscarinic and parasympathetic contractile responses in major diameter airways of dogs
Physiologist
Leff Ar., Muñoz NM., Murphy TM., Blake JS., Mack MM., Kelly E, (1988) Maturational effects and morphometric correlates of tracheal smooth muscle force generation in young swine
Am.Rev.Respir.Dis
Leff Ar., Muñoz NM., Ray D., Hernandez C., Solway j, (1988) Bronchoconstriction elicited by dry air hyperpnea in guinea pigs
Am.Rev.Respir.Dis
Leff, Ar., Muñoz, N.M., Stimler-Gerard, N.P., Mack, M.M., Blake, J., Kelly, E., Murphy, T.M., (1988) Role of platelet activating factor during immune degranulation with Ascaris Suum antigen in dogs
Am.Rev.Respir.Dis
Leff, A.R., Muñoz, N.M., NM., Bofman, J.D., White, S.R., Blake, J.S., Gleichi, G.J., (1988) Effect of epithelial removal and major basic protein of eosinophils on canine tracheal smooth muscle contraction to exogenously administered agonist in vivo
American review of Respiratory Disease
Kim, K.P., Rafter, J.D., Bittova, L., Han, S.K., Snitko, Y., Muñoz, N.M., Leff, A.R., Cho, W., (2001) Mechanism of human group V phospholipase A2 (cPLA2)-induced leukotriene biosynthesis in human neutrphils. A potential role of heparan sulfate binding in PLA2 internalization and degradation
Journal of Biological Chemistry
Leff Ar., Muñoz NM., White SR., Popovich KJ., Murphy TM., Blake JS., Mack MM.,, (1987) Homeostatic bronchodilating response during vasomotor and mediator-induced shock in swine
Fed.Proc
Leff Ar., Muñoz NM.,White SR., Stimler NP., Popovich KJ., Shioya T., Stimler-Gerard NP, (1986) Alpha-adrenergic augmentation of canine bronchial mast cell response to immune degranulation in vivo
Am.Rev.Respir.Dis
Leff Ar., Muñoz NM., Shioya T.,, (1986) Effect of resting smooth muscle length on contractile response in canine resistance airways in vivo
Fed.Proc
Leff Ar., Muñoz NM.,White SR., Sands MF., Murphy TM., Popovich Kj., Shioya T.,Baltopoulus G, (1986) Sympathetic homeostatic regulation of bronchomotor tone in swine
Fed.Proc
Leff AR., Muñoz NM.,Shioya T., Dame C., Bautina E.,, (1986) Potentiation of vagal efferent contractile response of canine tracheal smooth muscle by the thromboxane mimetic
U-46619.Fed.Proc
Leff Ar., Muñoz NM.,Shioya T., Primack S., Bautina E, (1985) Topographical distribution of airway diameter changes and smooth muscle contractile forces:relationship of airway caliber in situ and isometric smooth muscle contraction in vitro
Am.Rev.Respir
Leff, A.R., Muñoz, N.M., Stimler, N.P., Shioya, T., Tallet, J., Dame, C., Bautina, E., (1985) Augmentation of respiratory mast cell secretion of histamine caused by vagus nerve stimulation during antigen challenge
Am.Rev.Respir.Dis
Leff Ar., Muñoz NM., Tallet J., Fried R, (1984) Alpha- and beta-adrenergic response characteristics of canine trachealis musclein vitro
Fed.Proc
Dent, G., Muñoz, N.M., Zhu, X., Ruhlmann, E., Magnussen, H., Leff, A.R.,Rabe, K.F., (2000) Involvement of protein tyrosine kinases in activation of human eosinophis by platelet activating factor
Immunology
Zhu, X., Subbaraman, R., Jacobs, B., Sano, A., Boetticher, E., Muñoz, N.M., Leff, A.R., (2000) A surrogate method for assessment of human eosinophil activation by adhesion to B2 integrin
Journal of Immunological Methods
Muñoz, N.M., Kim, K.P., Han, S.K., Boetticher, E., Sperling, A.I., Sano, H., Zhu, X., Cho, W., Leff, A.R., (2000) Characterization of monoclonal antibodies specific for 14 KDa human group V secretory phospholipase A2(hVPLA2)
Hybridoma
Muñoz, N.M., Seventer G.A., Semnani, R.T., Leff A.R., (2000) Augmentation of LTC4 synthesis in human eosinophils caused by CD-3 stimulated Th2-like cell in vitro
American Journal of Physiology:Lung Cell Molecular Physiology
Zhu, X., Muñoz, N.M., Kim, K.P., Sano, H., Cho, W., Leff, A.R., (1999) Cytosolic phospholipase A2 activation is essential for B1 and B2 integrin-dependent adhesion of human eosinophils
Journal of Immunology
Muñoz, N.M., Mayer, D., Herrnreiter, A., Hamann, K., Neely, S.P., Leff, A.R.,, (1999) Augmentation of eosinophil degranulation of LTC4 secretion by integrin-mediated cell adhesion
Am.J.Physiol.:Lung Cell Mol.Physiol
Leff Ar., Muñoz NM., David AC.,Cavigelli M., Tallet J.,, (1984) Selective stimulation of porcine tracheal smooth muscle by superfusion method in situ
Fed.Proc
Leff, A.R., Muñoz, N.M., (1980) Alpa-adrenergic response of canine airways in vivo (Abstract)
Pharmacologist
Dent, G., Muñoz, N.M., Ruhman, E., Zhu, X., Leff, A.R.,Magnussen, H., Rabe, K.F., (1998) Protein kinase c inhibation enhances eicosanoid generation in PAF stimulated human eosinophil
American Journal of Respiratory Cell Molecular Biology
Leff, A.R., Muñoz, N.M., Shioya, T., (1988) Contractile properties and length-tension characteristics of major diameter airway of dogs in situ
American Review of Respiratory Disease
Leff Ar., Muñoz NM., Murphy TM., Moss J., Blake J., Mack MM, (1987) Mechanism of contractile response to platelet activating factor in canine trachealis in vivo
Physiologist
Leff Ar., Muñoz NM., Shioya T., Solway J, (1987) Distribution of airway contractile responses within the major bronchi during exogenous bronchoconstriction
Am.Rev.Respir.Dis
Leff Ar., Muñoz NM., White SR.,Popovich KJ., Mack MM, (1987) Multiple agonist interactions inhibiting tracheal smooth muscle relaxing response
Clin.Res
Zhu, X., Jacobs, B., Boetticher, E., Myou, S., Melitan, A., Sano H., Lambertino, A., Muñoz, N.M., Leff, A.R., (2002) Blockade of focal clustering and active conformation of B2-integrin-mediated adhesion of eosinophils to ICAM-1 caused by transduction of HIV TAT-dominant negative Ras
Journal of Immunology
Leff Ar., Muñoz NM.,Chang S-W., Mack M., Blake J., Voelkel N, (1987) A new method for selective stimulation of central and peripheral airways in isolated perfused rat lung
Am.Rev.Respir
Zhu, X., Jacobs, B., Boetticher, E., Myou, S., Melitan, A., Sano H., Lambertino, A., Muñoz, N,M., Leff, A.R., (2002) IL-5 induced integrin-adhesion of human eosinophils caused by ERK 1/2 adctivation of cPLA2
Journal of Leukocyte Biology
Leff Ar., Muñoz NM.,Garrity E., Stimler N., Tallet J., (1983) Sympathetic inhibition of bronchial smooth muscle response to mast cell degranulation
Fed.Proc
Leff Ar., Muñoz NM.,Fried R. Garrity E., (1983) Augmentation of tracheal smooth muscle contractile response after inhibition of prostaglandin synthesis in vitro
Fed.Proc
Leff Ar., Muñoz NM., Hendrix SG., (1982) Comparative distribution of smooth muscle contractile responses in canine trachea & bronchus in situ
Physiologist
Leff AR,. Muñoz NM., Hendrix SG.,, (1982) Physiological and pharcological response of canine bronchial smooth muscle measured isometrically in situ
Am.Rev.Respir.Dis
Leff Ar., Muñoz NM.,Szapary P.,Samsel R., Naurekas E., Lin A., Hernandez C., kellener M., Zimmerman A., Solway J., Hershenson M, (1992) Bronchoalveolar Lavage (BAL) Fluid From Immature Rats Increases Tropoelasatic (TE) Synthesis in Rat Lung Fibroblasts
FASEB J
Leff Ar., Muñoz NM., Cozzi PJ.,Vita AJ.,Hamann K., Baranowski S, (1992) Sequestration of promyelocytic (HL60) cells in the isolated-perfused pulmonary circulation of the rat inhibited by pre-treatment with cytochalasin
Am.Rev.Respir.Dis
Leff Ar., Muñoz NM., Vita A., Cozzi P., Hamann K., Baranowski S., Solway J, (1992) Effects of cultured human promyelocytic leukemia cells (HL60) on muscarinic responsiveness in guinea pig trachealis in vivo
Am.Rev.Respir.Dis
Leff Ar., Muñoz NM., Deitchman D., Garrity ER., Tallet J., Cavigelli M., Rajfer S, (1984) Comparative cardiovascular and airways smooth musle responses after beta-adrenergic blockade with bucindolol and propranolol
Fed.Proc.
Leff Ar., Muñoz NM., Hendrix SG., (1983) Distribution of parasympathetic and adrenergic contractile responses in canine trachea and bronchus in vitro
Am.Rev.Respir.Dis
Sano, A., Muñoz, N.M., Sano, H., Choi, J., Zhu, X., Jacobs, B., Leff, A.R., (1999) Inhibation of cPLA2 translocation and leukotriene C4 secretion by fluticasone propionate in exogenously activated human eosinophils
American Journal of Respiratory and Critical Care Medicine
Sano, H., Muñoz, N.M., Sano, A., Zhu, X., Herrnreiter, A., Choi, J., Leff, A.R., (1999) Upregulated surface expression of intracellular sequestered Ige receptors (FceRII/CD23) following activation in human peripheral blood eosinophils
Proceedings of the Association of American Physicians
Zhu, X., Hamann, K.J., Muñoz, N.M., Rubio, N., Mayer, D., Herrnreiter, A., Leff, A.R., (1998) Intracellular expression of FcyRIII (CD16) and its mobilization by chemoattractants in human eosinophils
Journal of Immunology
Leff A., Muñoz NM., (1981) Interrelationships between alpha- and beta-adrenergic agonists and histamine in canine airways
J.Allergy Clin. Immunol
Leff, A., Muñoz, N.M., (1981) Selective autonomic stimulation of canine trachealis with dimethylphenylpiperazinum (Abstract)
Journal of Applied Physiology
Leff, A., Muñoz, N.M., (1981) Evidence for two subtypes of alpha-adrenergic receptors in canine airways
Journal of Pharmacology and Experimental Therapeutics
Leff, A., Muñoz, N.M., (1981) Cholinergic and alpha-adrenergic augmentation of histamine-induced contraction of canine airway smooth muscle in vivo
Journal of Pharmacology and Experimental Therapeutics
Leff A., Muñoz NM., Alderman B., (1982) Measurement of airway response by isometric and non-isometric techniques in situ
J. Appl.Physiol
Leff A., Muñoz NM., Hendrix, SG., (1982) Sympathetic inhibition of histamine-induced contraction of canine tracheal muscle in vivo
J.Appl.Physiol
Leff, A., Muñoz, N.M., Hendriz, S.G., (1982) Comparative distribution of smooth muscle post-synaptic contractile response in canine trachea and bronchus in situ
Journal of Pharmacology and Experimental Therapeutics
Leff A., Muñoz NM.,Hendrix., SG, (1983) Physiological and Pharmacological response of canine bronchial smooth muscle measured isometrically in situ
J.Appl.Physiol
Leff A., Muñoz NM.,Hendrix., SG, (1983) Parasympathetic and adrenergic contractile responses in canine trachea and bronchus
J.Appl.Physiol
Leff AR., Muñoz NM., Garrity ER.,Stimler N., fried R.,, (1983) Response of bronchial smooth muscle to mast cell degtanulation in situ
J.Appl.Physiol
Leff A., Muñoz NM., Cera LM.,, (1984) Distribution of innervation and circulation in porcine cervical trachea
Am.J.Vet.Res
Leff A., Muñoz NM., Tallet J., Garrity ER., Cavigelli M., (1984) Selectivity of the intrinsic sympathimimetic activity of the B-adrenergic blocking drug bucindolol
J.Cardiovas.Pharmacol
Leff A., Muñoz NM.,Tallet J., David AC., Cavigelli M., Garrity ER, (1985) Augmentation of parasympathetic contraction in tracheal and bronchial airways by PGF2
J.Appl.Physiol
Leff A., Muñoz NM., Tallet J., David AC., Cavigelli M., Garrity ER, (1985) Autonomic response characteristics of porcine airway smooth muscle in vivo
J.Appl.Physiol
Leff A., Muñoz NM., Garrity ER., Stimler NP.,Tallet J., David AC.,, (1985) Sympathetic modulation of biochemical and physiological response to immune degranulation in canine bronchial airways in vivo
J.Clin.Invest
Leff A., Muñoz NM., Tallet J., Shoulberg N., (1986) Physiological antagonism caused by adrenergic stimulation of canine tracheal muscle
J.Appl.Physiol
Leff AR., Stimler NP., Muñoz NM., Shioya T., Tallet J., Dame C, (1986) Augmentation of respiratory mast cell secretion of histamine caused by vagus nerve stimulation during antigen challenge
J.Immunol
Tallet J., Muñoz NM., Fried R., Leff AR, (1986) Endogenous modulation of alpha-adrenergic contraction in canine tracheal muscle
J.Appl.Physiol
Muñoz NM., Shioya T., Murphy TM., Primack S., Dame C., Leff AR.,, (1986) Potentiation of vagal efferent contractile response of canine tracheal smooth muscle by the thromboxane mimetic
U-46619.J.Appl.Physiol
Solway J., Leff Ar., Dreshaj I., Muñoz NM., Igenito EP., Michaels D., Ingram RH Jr., Drazen JM., (1986) Circulatory heat sources for canine respiratory heat exchange
J.Clin.Invest
Shioya T., Muñoz NM., Leff AR, (1987) Effect of resting smooth muscle length on contractile response in canine resistance airways in vivo
J.Appl.Physiol
Leff AR., White SR., Muñoz NM., Popovich KJ., Shioya T., Stimler-Gerard NP, (1987) Parasympathetic involvement in PAF-induced contraction in canine trachealis in vivo
J.Appl.Physiol
White SR., Sands MF., Murphy TM., Muñoz NM., Blake J., Mack M.,Popovich K., Leff AR, (1987) Homeostatic regulation of airway smooth muscle tone by the catecholamine secretion in swine
J.Appl.Physiol
Shioya T., Solway J., Muñoz NM., Mack M., Leff AR.=, (1987) Distribution of airway contractile responses within the major diameter bronchi during exogenous brochoconstriction
Am.Rev.Respir.Dis
Shioya T., Muñoz NM., Leff AR., Pollak ER., (1987) Distribution of airway contractile responses in the major resistance airways in the dog
Am.J.Pathol
Muñoz NM., Leff AR.,Murphy TM., Hirshman CA., Blake J., (1987) Mechanisms of airway hyperreactivity in Basenji-Greyhound dogs
J.Appl.Physiol
White SR., Popovich KJ., Mitchelle RW., Koenig SM., Mack M., Muñoz NM.,, (1988) Antagonisms of relaxation to isoproterenol caused by postjunctional agonist interactions
J.Appl.Physiol
Popovich KJ., Sheldon G., Mack M., Muñoz NM., Denberg P., Blake J., White SR., Leff Ar.,, (1988) Role of platelets in contraction of canine tracheal muscle elicited by platelet activating factor in vitro
J.Appl.Physiol
Leff AR.,Muñoz NM., Shioya T., (1988) Comparative distribution of cholinomimetic and parasympathetic contractile responses in the major diameter airways of dogs
Pulm.Pharmacol
White Sr., Stimler-Gerard NP., Muñoz NM., Popovich KJ., Murphy TM., Blake J., (1989) Effect of beta-adrenergic blockade and sympathetic stimulation on canine bronchial mast cell response to immune degranulation in vivo
Am.Rev.Respir.Dis
Muñoz NM.,Chang S-W., Murphy Tm., Stimler-Gerard NP.,Blake J.,Mack M., Irvin C, (1989) Distribution of bronchoconstrictor responses in isolated-perfused rat lung
J.Appl.Physiol
Murphy TM., Muñoz NM.,Moss J., Blake J.,Mack MM., Leff AR, (1989) PAF-induced contraction of canine trachea mediated by 5-hydroxytryptamine in vivo
J.Appl.Physiol
Brofman JD., White SR., Blake JS., Muñoz NM.,Gleichi GJ., Leff AR, (1989) Epithelial augmentation of trachealis contraction by MBP of eosinophilis
J.Appl.Physiol
Muñoz NM.,Stimler-Gerard NP., Mack M., Blake J., Kelly E., Murphy T.,, Leff AR, (1989) Evidence for PAF secretion during immune degranulation in dogs
J.Appl.Physiol
White SR., Blake J., Murphy TM., Mack MM., Muñoz NM.,Leff Ar, (1989) Effect of vasomotor and mediator-induced hypotension on bronchomotor tone in swine
J.Appl.Physiol
Ray DW.,Hernandez C., Muñoz NM.,Leff AR., Drazen M., Solway J., Tachykinins, (1989) Tachykinins mediate bronchoconstriction elicited by isocapnic hyperpnea in guinca pigs
J.Appl.Physiol
Murphy TM., Mitchelle RW., Blake JS., Mack MM., Kelly E.,Muñoz NM., Leff AR., (1989) Expression of airway contractile properties and acetylcholinesterase activity in swine
J.Appl.Physiol
Shioya T.,Muñoz NM.,Leff AR, (1989) Translation of contractile force to constriction in major diameter canine airways in vivo
Am.Rev.Respir.Dis
Koenig, S.M., Mitchelle, R.W., Kelly, E., White, S.R., Leff, A.R.,Muñoz,N.M., Popovich, K.J., (1989) B-adrenergic relaxation of dog trachealis: contractile agonist-specific interaction
Journal of Applied Physiology
Muñoz NM.,Tutins C., Leff AR, (1989) Highly-sensitive determination of catecholamine and serotonin concentration in plasma by liquid chromatography/electrochemistry
J.Chromatography:Biomed Appl.Physiol
Brofman, J.D., White, S.R., Muñoz, N.M., (1990) Sympathetic secretory response to hypercapnic acidosis in swine
Journal of Applied Physiology
White, S.R., Ohno, S., Muñoz, N.M., Gleichi, G., Anrahams, C., Solway, J., Leff, A.R., (1990) Epithelium-dependent contraction of airway smooth muscle caused by eosinophil MBP
American Journal of Physiology:Lung Cell and Molecular Physiology
Murphy, T.M., Roy, L., Phillips, J.J., Mitchelle, R.W., Kelly, E.K., Muñoz, N.M., Leff, A.R., (1991) Effect of Maturation on topographical distribution of bronchoconstrictor responses in large diameter airways of young swine
American Review of Respiratory Disease
Muñoz NM.,Tutins C,.Leff AR, (1991) Bronchoconstriction elicited by platelet activating factor(PAF|) in isolated airways perfused with platelet-free solution
Am.J.Physiol.:Lung Cell. and Molec. Physiol
Murphy TM., Mitchelle RW., Roy LM., Mack M., Kelly EA., Muñoz NM.,Leff AR, (1991) Effect of maturational changes in myosin content and morphometry on airway smooth muscle contraction
Am.J.Physiol.:Lung Cell. and Molec. Physiol
Ikeda K., Mitchelle RW., Guest KA., Seow CY., Kirchhoff CF.,Muñoz NM.,Murphy TM., Leff AR.,, (1992) Ontogeny of shortening velocity in porcine trachealis
Am.J.Physiol:Lung Cell. Molec.Physiol
Covert, R.F., Schreiber, M.D., Leff, A.R., White, S.R., Muñoz, N.M., Torgeson, J., (1993) Oxygen metabolism and catecholamine secretion during anesthesia in lambs
Journal of Developmental Physiology
Muñoz, N.M.,Hamann, K.J., Vita, A., Cozzi, P., Baranowski, S., Soloway, J., Leff, A.R., (1993) Activation of tracheal smooth muscle responsiveness by fMLP-treated HL-60 cells and neutrophils
American Journal of Physiology:Lung Cellular, Molecular Physiology
Muñoz NM.,Zak R., Panetierri R., Wiesner R., Leff AR.,, (1993) Changes in levels of mRNA endoding myosin heavy chain in porcine trachealis during ontogenesis
Am.J.Respir.Cell.Mol.Biol
Muñoz NM.,Strek ME., White SR., Ndukwu M., Williams FS., Vita AJ., Leff Ar., Mitchelle RW., (1993) Physiological significance of epithelial removal on guinea pig tracheal smooth muscle response to acetycholine
American Review of Respiratory Disease
Padrid PA., Wolf R., Spaethe S., Muñoz NM.,Finucane T. Solway J., Leff AR, (1993) Selective attenuation by 5-lipoxygenase blockade of peripheral airway hyperresponsiveness and edema caused by activated alveolar macrophages
Am.Rev.Respir.Dis
Hamann KJ.,Strek ME., Baranowski SL., Muñoz NM.,Williams FS., White SR., Leff AR, (1993) Effects of activated eosinophils cultured from human cord blood on guienea pig trachealis in situ
Am.J.Physiol.:Lung Cell Mol. Physiol
Muñoz, N.M.,Vita, A.J., Neely, S.P., McAllister, K., Spaethe, S., White, S.R., Leff, A.R., (1994) Beta-adrenergic modulation of fMLP-stimulation and secretion of cosinophil peroxidase and leukotriene C4
Journal of Pharmacological Experimental Therapy
Rabe KF., Muñoz NM.,AJ Vita., BE Morton, (1994) Contraction of human bronchial smooth muscle caused by activated human eosinophils
Am.J.Pysiol.:Lung Cell. Mol. Physiol
Galena S.,Muñoz NM.,KF Rabe.,, (1995) Assessment of agonist- and cell- mediated responses in airway microsections by computerized videomicrometry
Am.J.Physiol.: Lung Cell.Mol.Physiol
Muñoz, N.M., (1995) Blockade of eosinophil migration by 5-lipoxygenase and cycloxygenase inhibition in explanded guinea pig trachealis
American Journal of Physiology
Muñoz NM.,KF Rabe., Aj Vita., K McAllister., D Mayer., Weiss M., AR Leff, (1995) Paradoxical blockade of beta-adrenergically mediated inhibition of stimulated eosimophil secretion by salmeterol
J.Pharmacol.Exp.Ther
Muñoz NM.,Rabe KF., Neely SP., Herrneiter A., Zhu X., McAllister K., Mayer D., Magnussen H., Galens S., Leff AR, (1996) Eosinophil VLA-4 binding to fibrinection causes augmented narrowing of human bronchial explants through 5-lipoxygenase activation
Am.J.Physiol.:Lung Cell Mol.Physiol
Zhu X., Muñoz NM.,Rubio N., Herrnreiter A., Mayer D., Douglas I., Leff AR, (1996) Quantitation of the cytosolic phospholipase A2(typeIV) in isolated human perpheral blood eosinophils by Sandwich-Elisa
J.Imm.Meth
Muñoz, N.M., Douglas I., Mayer D., Herrnreiter, A., Zhu X., Leff, A.R., Rabe, K.F., (1997) Eosinophil chemotaxis inhibited by 5 lipoxygenase blockade and leukotriene receptor antagonism
American Journal of Respiratory and Critical Care Medicine
Mitchelle, R.W., Ruhlman, E., Magnussen, H., Muñoz, N.M., Leff, AR., Rabe, K.F., (1997) Conservation of bronchiolar wall area during constriction and dilation of human airways
Journal of Applied Physiology
Saito, M., Sato, R., Muñoz, N.M., Herrnreiter, A., Oyaizu, M., Hiroyoshi, K., Narahashi, R., Leff, A.R., (1997) Regulation of granular exocytosis by Ca2+ Activated K+ channel in human eosinophils
Am.J.Physiol.: Lung Cell Mol. Physiol
Leff, A.R., Herrnreiter, A., Naclerio, R.M., Baroody, F.M., Handley, D.A., Muñoz, N.M., (1998) Effect of enantiomeric forms of albuterol on stimulated secretion of granular protein from human epsinophils
Pulmonary Pharmacology and Therapy
Leff, Ar., Muñoz, N.M., Padrid, P.A., Wolf, R., Spaethe, S., Kalk, A., Finucane, T., (1992) Selective attenuation by 5-lipoxygenase blockade of peripheral airway hyperresponsiveness and edema caused by activated alveolar macrophages
American Review of Respiratory Disease
Leff, A.R., Muñoz, N.M., Vita, A.J., Neely, S., White, S.R., (1993) Modulation of human eosinophil function by B-adrenergic receptor stimulation
American Review of Respiratory Disease
Leff, A.R., Muñoz, N.M., Vita, A.J., (1993) Blockade of fMLP-induced eosinophil chemotaxis caused by 5-lipoxygenase and cycloxygenase inhibition
American Review on Respiratory Disease
Leff, A.R., Muñoz, N.M., Panettierri, R.A., Eszterhas, A., Guest, K., (1993) Myosin expression but not smooth muscle specific actin is modulated in porcine airway smooth muscle during maturation
American Review of Respiratory Disease
Leff, A.R., Muñoz, N.M., Rabe, K.F., Mitchelle, R.W., Hamann, K.J., Schreiber, M., Vita, A.J., Torgerson, L., Magnussen, H., (1993) Direct and augmented contraction of human bronchi caused by cultured eosinophils and HL-60 cells in vitro
American Review of Respiratory Disease
Leff Ar., Muñoz NM., Strek ME., White SR., Ndukwu IM., Williams FS., Vita AJ., Mitchelle RW, (1993) Physiological significance of epithelial removal on guinea pig tracheal smooth muscle
Am.Rev.Respir.Dis
Leff, A.R., Muñoz, N.M., Galens, S.A., Rabe, K.F., Morton, B., McAllister, K., Magnussen, H., (1994) Physiological and pharmacological response characteristics of explanted guinea pig airway measured by automated video-microscopy
American Review of Respiratory Disease
Leff, A.R., Muñoz, N.M., Vita, A.J., McAllister, K., Mayer, D., Magnussen, H., (1994) MOdulatory effect of b-receptor agonists on human peripheral blood eosinophil function
American Review of Respiratory Disease
Leff, A.R., Muñoz, N.M., Mayer, D.,McAllister, K., (1994) Enhancement of eosinophil function by GM-GSF and blockade by B-adrenergic agonist
American Review of Respiratory Disease
Leff Ar., Muñoz NM.,, (1995) New method for real-time measurements of changes in lumenal area of microsection explants of airways by videomicrometry
Asplen Lung Conference:Chest
Leff, A.R., Muñoz, N.M., Zhu, X., Rabe, K.F., Hernreiter, A., (1995) Passive sensitization of human peripheral blood eosinophils: effect on CD23/FceEII expression and eosinophil degranulation
American Journal of Respiratory and Critical Care Medicine
Leff, A.R., Muñoz, N.M., Rabe, K.F., Neely, S.P., Herrnreiter A., Zhu X., McAllister, K., Mayer, D., (1995) Eosinophil VLA-4 binding to fibronection causes augmented narrowing of human bronchial explants through 5-lipoxygenase activation
American Journal of Respiratory and Critical Care Medicine
Leff, A.R., Muñoz, N.M., Rabe, K.F., Dent, G., Wagner, K., (1995) Inhibition of allergen-induced contraction of human airways in vitro by a monoclonal anti-human IgE antibody
American Journal of Respiratory and Critical Care Medicine
Leff, A.R., Muñoz, N.M., Rabe, K.F., Ruhlman, E., Dent, G., Heusser, C.H., Einsle, K., Magnussen, H., (1995) Assessment of anti-IgE mediated responses of passively sensitized human airways in vitro by videomicroscopy and the role of IgE
American Journal of Respiratory and Critical Care Medicine
Leff Ar., Muñoz NM., Douglas IS.,, (1995) Phospholipase A2 regulation of eicosanoid metabolism in fibronectin ligated eosinophil
Am.J.Respir.Crit.Care.Med
Leff Ar., Muñoz NM.,Herrnreiter A., RAbe KF., Mayer D.,Zhu X., Douglas I., Magnussen H., Heusser Ch, (1995) Induction by interleukin (IL)-1 augments eosinophil secretion and lumenal narrowing of explanted human airways
Am.J.Respir.Crit.Care.Med
Rabe, K.F., Morton, B.E., Dent, G., Muñoz, N.M., Waner, K., Leff, A.R., Magnussen, H., Heusser Ch, (1995) A monoclonal anti-human lgE blocks antigen-induced contractions of sensitized human airway in vitro
ERJ
Muñoz, N.M., Douglas, I., Mayer, D., Herrnreiter, A., Leff, A.R., (1996) Zileuton inhibits eosinophil migration caused by FMLP in guinea pig tracheal explants
American Journal of Respiratory and Critical Care Medicine
Muñoz, N.M., Leff, A.R., Zhu, X., Douglas, I., (1996) Highly sensitive determination of human cytosolic phospholipase A2 content in eosinophils by sandwich-ELISA
American Journal of Respiratory and Critical Care Medicine
Muñoz, N.M., Leff, A.R.,, (1996) Adhesion of eosinophils to fibronectin causes translocation of cytoplasmic PLA2 to nuclear membrane
American Journal of Respiratory and Critical Care Medicine
Muñoz, N.M., Leff, A.R., Douglas, I., (1996) Priming of activation of the 85 kD cytoplasmic isoform of PLA3 by ligation with fibronectin in human eosinophils
American Journal of Respiratory and Critical Care Medicine
Muñoz, N.M., Leff, A.R., Dent, G., Ruhlman, E., Zhu X., Magnussen, H., Rabe, K.F., (1996) Protein kinase C inhibition enhances eicosanoid generation in PAF-stimulated human eosinophil
American Journal of Respiratory and Critical Care Medicine
Muñoz N.M., Leff A.R., (1996) Eosinophil interaction with cultured HUVEC augments eosinophil functions
ASPET Great Lake Chapter Meeting
Muñoz, N.M., Leff, A.R., Rabe, K.F., Zhu, X., Dent, G., Rubio, N., Magnussen, H., (1997) Tyrosine-specific protein phosphorylation in PAF-activated human peripheral blood eosinpphils
American Journal of Respiratory and Critical Care Medicine
Muñoz, N.M., Leff, A.R., Dent, G., Zhu, X., Ruhlman, E., (1997) Effects of protein tyrosine kinase inhibitors on Effects of protein tyrosine kinase inhibators on platelet activating factor-induced respiratory burst and leukotriene production in human eosinophils
American Journal of Respiratory and Critical Care Medicine
Muñoz, N.M., Leff, A.R., Douglas, I., Mayer, D., Herrnreiter, A., Zhu, X., (1997) Eosinophil chemotaxis inhibited by 5-lipoxygense blockade and leukotriene receptor antogonism
American Journal of Respiratory and Critical Care Medicine
Muñoz, N.M., Leff, A.R.,Saito, M., Sato, R., Oyaizu, M., Kasugai, H., Narashi, T., (1997) Blockade of Ca2+ -activated K+ channels by epinastine in stimulated human eosinophils
American Journal of Respiratory and Critical Care Medicine
Muñoz, N.M., Leff, A.R., Saito, M., Saito, R., Herrnreiter, A., Oyaizu, M., Kasugai, H., Narashi, T., (1997) Association of granular exocytosis by CA2+ -activated K+ channels in human eosinophils
American Journal of Respiratory and Critical Care Medicine
Muñoz, N.M., Leff, A.R., Herrnreiter, A., Naclerio, R., Baroody, F., Handley, D.A., (1997) Effects of enantiomeric forms of albuterol on stimulated secretion of granular protein from human eosinophils
American Journal of Respiratory and Critical Care Medicine
Muñoz, N.M., Leff, A.R., (1997) Assessment of agonist responses in human bronchus by video-micrometry:role of epithelium
American Journal of Respiratory and Critical Care Medicine
Muñoz, N.M., Leff, A.R., Zhu, X., Hamann, K.J., Rubio, N., Mayer, D., Herrnreiter, A., (1997) Intracellular FcGammarRIII(CD16) expression and translocation to cell surface in stimulated human eosinophils
American Journal of Respiratory and Critical Care Medicine
Muñoz NM.,Leff AR.,Zhu X., Rubio N., Douglas I, (1997) Localization and functional role of 84 kDa type IV and 14 kDa type II PLA2 on LTC4 generation by stimulated human eosinophils
American Journal of Respiratory and Critical Care Medicine
Muñoz NM.,Leff AR.,Douglas I., Mayer D., Herrnreiter A., Zhu X., Hamann K., Rubio N, (1997) Augmented secretion of LTC4 caused by human eosinophil binding to cultured human umbilical vein endothellial cells
American Journal of Respiratory and Critical Care Medicine
Muñoz NM.,Leff AR.,Semnam RT., van seventer GA, (1997) Cytokines from activated Th2 cells augment secretion of LTC4 from human eosinophils
J.Invest.Med
Muñoz, N.M., Leff, A.R., van Seventer, G.A., (1997) Endogenous cytokines from activated Th2-like cells caused augmented eosinophilic secretion of granular protein and LTC4
Berlin.European Respiratory Journal
Muñoz, N.M., Leff, A.R., Sano, A., Sano, H., (1998) Inhibition of cPLA2 translocation and leukotriene C4 synthesis by fluticasone proprionate in activated human eosinophils
Eurupean Respiratory Journal
Muñoz, N.M., Leff, A.R., Zhu, X., Choi, J., (1998) Generation of soluble factors from cultured human Th2-like cells augmented LTC4 secretion in human eosinophils
American Journal of Respiratory and Critical Care Medicine
Muñoz, N.M., Leff, A.R., Zhu, X., Choi, J., (1998) Regulatory role of secretory phospholipase A2(sPLA2) on eosinophil functions and Mac-1 expression by stimulated human eosinophils
American Journal of Respiratory and Critical Care Medicine
Muñoz, N.M., Leff, A.R., Sano, A., Sano, H., Mayer, D., Zhu, X., (1998) Apoptosis and direct inhibition of stimulated secretion of leukotriene C4 in human eosinophils caused by fluticasone propionate (FP)
American Journal of Respiratory and Critical Care Medicine
Muñoz, N.M., Leff, A.R., Douglas, I.S., Mayer, D., (1998) Exogenous eotaxin augments cytokine-mediated human eosinophil LTC4 secretion
American Journal of Respiratory and Critical Care Medicine
Muñoz, N.M., Leff, A.R., Sano, H., Zhu, X., Sano, A., (1998) Quantitation and localization of CD23/FceRII in human eosinophils isolated from peripheral blood
American Journal of Respiratory and Critical Care Medicine
Muñoz, N.M., Leff, A.R.,Sano, H., Zhu, X., Sano, A., Choi, J., (1999) Tyrosine protein phosphorylation caused by eosinophil VLA-4 (CD49d) binding to immobilized soluble fibronectin
American Journal of Respiratory and Critical Care Medicine
Muñoz, N.M., Leff, A.R., Sano, A., Sano, H., Choi, J., Zhu, X., Jacobs, B., (1999) Selective inhibition of cPLA2-induction of LTC4(LTC4) synthesis by corticosteroid in IL-5 primed human eosinophils
American Journal of Respiratory and Critical Care Medicine
Muñoz, N.M.,Leff, A.R., Zhu, X., Choi, J., Sano, H., Moo-Young, T., (1999) Adhesion to vascular cell adhesion molecule-1 activates cytosolic PLA2 in human eosinophils
American Journal of Respiratory and Critical Care Medicine
Muñoz, N,M., Leff, A.R., Choi, J., Zhu, X., Sano, H., Kim, K.P., (1999) Role of phosphatidylcholine-specific phospholipase C (PC-PLC) in stimulated eosinophil granular protein and LTC4 synthesis in human eosinophils
American Journal of Respiratory and Critical Care Medicine
Muñoz, N.M., Leff, A.R.,Rabe, K.F., Sano, H., Choi, J., Herrnreiter, A., (1999) Augmentation of eosinophil degranulation and LTC4 secretion caused by integrin-mediated endothelial cell adhesion
American Journal of Respiratory and Critical Care Medicine
Muñoz, N.M., Leff, A.R., Kim, k.P., Han, S.K., Cho W., Zhu, X., (1999) Role of 14 kDa type V secretory PLA2 (sPLA-V) on synthesis of 5-lipoxygenase and cycloxygenase metabolites in activated human neutrophils
American Journal of Respiratory and Critical Care Medicine
Muñoz, N.M., Leff, A.R.,.Zhu, X., Kim, K.P., Sano, H., Choi, J., (1999) Cytosolic phospholipase A2 is phosphorylated during IL-5 priming of human eosinophils
American Journal of Respiratory and Critical Care Medicine
Muñoz, N.M., Leff, A.R.,Kim, K., Han, S., Cho, W., (1999) Functional role of Type II secretory PLA2(sPLA2) and Type V sPLA2 on release of eosinophil-derived neurotoxin (EDN) and LTC4 synthesis from activated eosinophils
American Journal of Respiratory and Critical Care Medicine
Muñoz, N.M., Leff, A.R., Zhu, X., kim, K.P., Sano, H., Choi, J., (1999) Regulation of B2 integrin-dependent adhesion of human eosinophils by cytosolic phospholipase A2
American Journal of Respiratory and Critical Care Medicine
Muñoz, N.M., Leff, A.R.,Zhu, X., Cho, W., Kim, K.P., (1999) Translocation of cytosolic phospholipase A2 (cPLA2) to nuclear membrane in stimulated human neutrophils
American Journal of Respiratory and Critical Care Medicine
Muñoz, N,M., Leff, A,R., Boetticher, E., Kimm, K.P., Hanm, S.K., Sperling, A., Sano, H., Zhu, X., Cho, W., (2000) Development and characterization of monoclonal antibody (mAb) specific for 14 kDa group V-secretory phospholipase A2 (sPLA2-V)
American Journal of Respiratory and Critical Care Medicine
Muñoz, N.M., Leff, A.R.,Zhu, X., Sano, H., Jacobs, B., Sano A., Boetticher, E., (2000) Regulation of B2-integrin-dependent adhesion of human eosinophils by endogenous production of platelet activating factor (PAF)
American Journal of Respiratory and Critical Care Medicine
Muñ±oz, N.M., Leff, A.R.,Zhu, X., Sano, H., Kim, K.P., Jacobs, B., Sano, A., Boetticher, E., Cho, W., (2000) Mechanism of IL-5 priming of LTC4 synthesis in fMLP-activated human eosinophils
American Journal of Respiratory and Critical Care Medicine
Muñoz, N.M., Leff, A.R.,Kim, K.P., Jacobs, B., Sano, A., Boetticher, E., Sano, H., Zhu, X., Cho, W., (2000) A novel mechanism for synthesis of eosinophil cysteinyl leukotriene C4 (LTC4) by group V-secretory phospholipase A2 (sPLA2-V)
American Journal of Respiratory and Critical Care Medicine
Muñoz, N.M., .Leff, A.R.,.van Seventer GA., Semnani, R.T., (2000) Selective augmentation of LTC4 synthesis in human eosinophils caused by CD3-stimulated TH-2-like cells in vitro
American Journal of Respiratory and Critical Care Medicine
Muñoz, N.M., Leff, A.R.,Sano, H., Zhu, X., Sano, A., Boetticher E., Wada, A., (2000) Role of mitogen-activated protein kinase phosphorylation in eosinophil adhesion to fibronectin
American Journal of Respiratory and Critical Care Medicine