Researches:

Article title: Genotyping of respiratory syncytial virus among influenza‐like illness and severe acute respiratory infection cases of children in the Philippines from 2006 to 2016
Authors: Jonjee Calaor-Morin, Vina Lea Arguelles, Janiza Lianne Foronda, Alvin Tan, Evelina Lagamayo, Clyde Dapat, Socorro Lupisan
Publication title: Influenza and other respiratory viruses 16(5):942-951, 2022

Abstract:
Objective: Respiratory syncytial virus (RSV) is a leading cause of severe lower respiratory infection, and therefore, a major threat to global health. This study determined the epidemiological and molecular characteristics of RSV among cases of influenza-like illness (ILI) and severe acute respiratory infection (SARI) among children in the Philippines.

Method: The study included archived nasopharyngeal swab and oropharyngeal swab samples collected from patients under the age of five who are presented with ILI or SARI for the period of 2006-2016. Swabs were examined for RSV subgroup by multiplex real-time qRT-PCR. Partial genome sequencing and phylogenetic analyses of the second hypervariable region (HVR) of the G gene were used to determine the genotype of RSV isolates.

Results: A total of 1036 representative samples from all sites were selected and tested. Of these samples, 122 were RSV-positive at 11.8% prevalence rate, and 58.2% (71/122) were classified as RSV-A. Six genotypes were identified, which include NA1 (27/122, 22.1%), ON1 (5/122, 4.1%), GA2 (1/122, 0.8%), and GA5 (1/122, 0.8%) for RSV-A; and BA2 (13/122, 10.7%) and BA9 (1/122, 0.8%) for RSV-B. Most RSV-related cases were significantly associated with clinical characteristics such as runny nose (88.1% RSV vs. 11.9% non-RSV: p value = 0.021), pneumonia (80.6% RSV vs. 19.4% non-RSV; p value = 0.015), and bronchitis (71.7% RSV vs. 28.3% non-RSV; p value < 0.001). Increased RSV-related cases were observed among children below 24 months old.
Full text available upon request to the author/s.

Article title: Serotype Identification of Human Adenoviruses Associated with Influenza-Like Illnesses in the Philippines from 2006 to 2012 by Microneutralization and Molecular Techniques
Authors: Catherine Calzado-Dacasin, Janiza Lianne Foronda, Vina Lea Arguelles, Chona Mae Daga, Marie Therese Quimpo, Socorro Lupisan, Clyde Dapat, Mariko Saito, Michiko Okamoto, Pia Marie Albano, Hitoshi Oshitani
Publication title: International Journal of Infectious Diseases 117:326-333, April 2022

Abstract:
Objectives
Human adenoviruses (HAdV) are known to cause a wide range of diseases including acute respiratory infections, conjunctivitis, and acute gastroenteritis. In this study, we aimed to determine the serotypes of HAdV in patients with influenza-like illness (ILI) in the Philippines from 2006-2012 and to describe the demographic and epidemiological characteristics of patients who tested positive for HAdV.

Methods
Between 2006 and 2012, the Philippine National Influenza Centre detected HAdV in 1294 samples of patients with ILI. Serotype determination was done in select samples using microneutralization, polymerase chain reaction (PCR), and sequencing methods.

Results
A total of 8 serotypes were identified (HAdV 1–7 and 11), with HAdV-2 (27.8%), and HAdV-3 (27.8%) being the most prevalent. The majority of HAdV infections were found in children below 5 years of age (79.9%).

Conclusions
The identification of HAdV circulating serotypes may serve as guide for designing disease intervention and control strategies and will provide important information regarding the contribution of this virus to respiratory infections, particularly in children, which remain a public health burden in the Philippines.
Full text link https://tinyurl.com/45frj3mb

Article title: Human adenoviruses associated with severe acute respiratory infections in the Philippines
Authors: C. Calzado, V. L. Arguelles, J. Morin, M.T. Quimpo, H. Base, et al.
Publication title: International journal of infectious diseases: IJID: official publication of the International Society for Infectious Diseases 101:517-518, December 2020

Abstract:
No available
Full text link https://tinyurl.com/2p83fnss

Article title: Molecular epidemiology of coxsackievirus A6 causing hand-foot-and-mouth disease in the Philippines, 2012–2017
Authors: Janiza M. Foronda
Publication title: International journal of infectious diseases: IJID: official publication of the International Society for Infectious Diseases 101:499, December 2020

Abstract:
No abstract
Full text link https://tinyurl.com/4tk88322

Article title: Epidemiological and clinical comparison of influenza virus infections including meteorological parameters affecting influenza activity in the Philippines, 2006–2012
Authors: V.L.F. Arguelles, Janiza M. Foronda, M. Inobaya
Publication title: International journal of infectious diseases: IJID: official publication of the International Society for Infectious Diseases 79:95, February 2019

Abstract:
No available
Full text link https://tinyurl.com/42x2tm78